DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr1 and Igsf9b

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	XP_011240777.1	Gene:	Igsf9b / 235086	MGIID:	2685354	Length:	1443	Species:	Mus musculus

Alignment Length:	222	Identity:	55/222 - (24%)
Similarity:	91/222 - (40%)	Gaps:	39/222 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 NLLPYFDFDVPRNLTVTVGQTGFLHCRVERLGDKDVSWIRKRDLHILTAGGTTYTSDQRFQVLRP 114
            |..|.|....|:.:....|.:..:.|.........|:|:::         ||...:..::||  .
Mouse   138 NAPPTFTETPPQYIEAKEGGSITMTCTAFGNPKPIVTWLKE---------GTLLGASAKYQV--S 191

  Fly   115 DGSANWTLQIKYPQPRDSGVYECQINTEPKMSLSYTFNVVELKAEIFG-PSDLMVKTGSDINLTC 178
            |||    |.:......|.|.|.|:..:....::..|..:|:....|.. |.::.|....|..|||
Mouse   192 DGS----LTVTSVSREDRGAYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTC 252

  Fly   179 KIMQGPHELGNI--FWYKGSEMLDGKGENEIDSSMARIRVEDDWTDGLTSRLKIKRAMPGDTGNY 241
            :....|   ||:  .||...|.:..:.:.::     |:|:..|.|      |.|.|..|.|.|.|
Mouse   253 RAEAYP---GNLTYTWYWQDENVYFQNDLKL-----RVRILIDGT------LIIFRVKPEDAGKY 303

  Fly   242 TCVPT----VAKTSSVYVHVIIGEHPA 264
            ||||:    .:.::|.|:.|   ::||
Mouse   304 TCVPSNSLGRSPSASAYLTV---QYPA 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	18/94 (19%)
		IG_like	60..150	CDD:214653	17/89 (19%)
		IG_like	163..257	CDD:214653	29/99 (29%)
		Ig	174..244	CDD:143165	21/71 (30%)
Igsf9b	XP_011240777.1	Ig	43..117	CDD:319273
		I-set	141..227	CDD:369462	20/100 (20%)
		Ig	231..323	CDD:386229	30/105 (29%)
		Ig	<355..416	CDD:386229
		Ig	440..504	CDD:319273
		FN3	512..607	CDD:238020
		FN3	623..705	CDD:238020
		PHA03247	<900..1248	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900