DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr1 and zig-8

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_499714.1	Gene:	zig-8 / 176732	WormBaseID:	WBGene00006985	Length:	268	Species:	Caenorhabditis elegans

Alignment Length:	230	Identity:	67/230 - (29%)
Similarity:	109/230 - (47%)	Gaps:	29/230 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 LTVTVGQTGFLHCRVERLGDKDVSWIRKRDLHILTAGGTTYTSDQRFQVLRPDGSAN-WTLQIKY 126
            :.|......:|||.|....:.:::|.|..|..:||||..|:|.|.|:||.:.  ||| |.|.::.
Worm    45 VNVVAENPAYLHCSVPPDAEHEIAWTRVSDGALLTAGNRTFTRDPRWQVSKK--SANIWVLNLRR 107

  Fly   127 PQPRDSGVYECQINTEPKMSLSYTFNVVELKAEIFGPSDLMVK--------TGSDINLTCKI--M 181
            .:.:|||.|.|:||  .|.:..|...:..|:..:..||.|..|        :|.::.|.|.:  .
Worm   108 AEQQDSGCYLCEIN--DKHNTVYAVYLKVLEPPLPSPSSLQKKSTKLMANMSGDEVVLNCTVTST 170

  Fly   182 QGPHELGNIFWYKGSEMLDGKGENEIDSSMARIRVEDDWTDGLTSRLKIKRAMPGDTGNYTCVPT 246
            ....|:.::.|.:     ||...|..|:....::|:.| ...:...::|::|...|.|||.|..:
Worm   171 DKDEEVLDVVWTR-----DGNTINFNDTEKYILKVKRD-AGVVIETMRIRKATMEDDGNYACEHS 229

  Fly   247 VAKTSSVYVHVIIGEHPAAMQHNSSSNSNSFYCGI 281
            ..|.|.: ||:    :.|..|   :|||.:|.|.|
Worm   230 QQKASQI-VHI----NKAEAQ---TSNSATFPCSI 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	32/91 (35%)
		IG_like	60..150	CDD:214653	31/87 (36%)
		IG_like	163..257	CDD:214653	25/103 (24%)
		Ig	174..244	CDD:143165	16/71 (23%)
zig-8	NP_499714.1	IG_like	55..134	CDD:214653	31/82 (38%)
		Ig	55..129	CDD:143165	30/77 (39%)
		ig	158..229	CDD:278476	18/76 (24%)
		IG_like	158..227	CDD:214653	17/74 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I7153
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	82	1.000	Inparanoid score	I3769
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000207
OrthoInspector	1	1.000	-	-		oto19279
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23279
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16925
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.990