DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr1 and nitr1l

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_938161.2	Gene:	nitr1l / 170986	ZFINID:	ZDB-GENE-020225-7	Length:	316	Species:	Danio rerio

Alignment Length:	341	Identity:	76/341 - (22%)
Similarity:	118/341 - (34%)	Gaps:	103/341 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 STTTISPSNLLPYFDFDVPRNLTVTVGQTG---FLHCRVERLGDKDVSWIRK----RDLHILTA- 98
            |:|....|.|      :|.:...|.:...|   .|.|...||.....:|.::    :.|.|::.
Zfish    10 SSTIFCSSGL------EVVQENNVKIAAAGEEVNLTCTFIRLVQATKAWFKQTADGKSLQIVSLY 68

  Fly    99 --GGTTYT--SDQRFQVLRPDGSANWTLQIKYPQPRDSGVYECQINTEPKMSLSYTFNVVELKAE 159
              |...::  |:..|.|::.||..|  |.|...:|.||..|.|.|:|      .|||.:......
Zfish    69 SNGKPVWSNISENHFNVMKGDGYFN--LTILKTKPSDSATYYCVIST------FYTFGMGSGTRL 125

  Fly   160 IFGPSDL----------MVKTGSDINLTCKIM----QGPHELGNIFWYKGSE-----MLDGKGEN 205
            :...:|.          .|..|..:||.|.|.    :|.|   :|:|:|.|.     :|..|||.
Zfish   126 LVRAADRNTTLHQSLIDTVDPGDSVNLQCSIFTESCEGDH---SIYWFKQSSGDSEGVLYTKGER 187

  Fly   206 E---IDSSMARIRVEDDWTDGLTSRLKIKRAMPGDTGNYTC-VPTVAKTSSVYVHVIIGE----- 261
            .   .||:       :..|......|........|:|.|.| |.|..:       ::||.
Zfish   188 NGRCKDST-------ESQTQSCVYSLHKNNISRSDSGIYYCAVATCGQ-------ILIGRGTQLN 238

  Fly   262 ------HPAAMQHNSSSNSNSFYCGICCMLLSIVSCCLQHFYETGCGYLHAAAALAKSAGLGPPK 320
                  :||.:   :|..:|..:..: .:.|.|..|..|.                      .|.
Zfish   239 IRESDFNPALL---ASGITNVIFLAL-VVFLGIKLCRSQI----------------------KPS 277

  Fly   321 RATLTTSETGISAAEV 336
            .|..|..|.|::.|.:
Zfish   278 AAQATEDEDGLNYASI 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	29/106 (27%)
		IG_like	60..150	CDD:214653	25/101 (25%)
		IG_like	163..257	CDD:214653	27/116 (23%)
		Ig	174..244	CDD:143165	22/82 (27%)
nitr1l	NP_938161.2	V-set	30..128	CDD:311561	27/105 (26%)
nitr1l	NP_938161.2	V-set	143..240	CDD:311561	28/113 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1457433at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010