DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr1 and AgaP_AGAP008943

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	XP_319698.3	Gene:	AgaP_AGAP008943 / 1279913	VectorBaseID:	AGAP008943	Length:	685	Species:	Anopheles gambiae

Alignment Length:	268	Identity:	66/268 - (24%)
Similarity:	99/268 - (36%)	Gaps:	63/268 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 GLLN---WLIGWLLLLSMVLLRGYNAALAPTPPTTSTT------TISPSNLLP-------YFDFD 58
            |:||   ..||.:.||:..:|.| .|:|..|....|..      .|.| |.:|       :|...
Mosquito    80 GVLNAYETFIGRVTLLNNDILYG-KASLNLTSIRESDNGWYECKVIFP-NRVPNKRNNGTWFHIS 142

  Fly    59 V---------PRNLTVTVGQTGFLHCRVERLGDKDVSWIRKRDLHILTAGGTTYTSDQRFQVLRP 114
            |         |.|.||..|...|.||.|:......|.|. |.::.:|......:.|     ::.|
Mosquito   143 VLGGTLLRIPPVNQTVLEGDPAFFHCVVQNPETMFVEWY-KDNVSLLEYYDLAHRS-----MMGP 201

  Fly   115 DGSANWTLQIKYPQPRDSGVYECQI--NTEPKMSLSYTFNVVELKAE-IFGPSDLMVKTGSDINL 176
            |||    |.|...|..|.|.:.|::  :.....|.|...| |:.||: ::.|.::.:..|....|
Mosquito   202 DGS----LTINPTQMSDLGFFTCEVRNSANDTQSASAYLN-VQYKAKVVYAPKEVYIPFGESAVL 261

  Fly   177 TCKIMQGPHELGNIFWYKGSEMLDGKGENEI----DSSMARIRVEDDWTDGLTSRLKIKRAMPGD 237
            .|.....| .|.|:.|.|...:.|......:    :.|:...:|:|                 ..
Mosquito   262 NCHFRSNP-PLKNLRWEKDGFLFDPYNVQGVFYNRNGSLQFDKVDD-----------------SH 308

  Fly   238 TGNYTCVP 245
            .|.|:|.|
Mosquito   309 AGRYSCTP 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	28/105 (27%)
		IG_like	60..150	CDD:214653	26/91 (29%)
		IG_like	163..257	CDD:214653	17/87 (20%)
		Ig	174..244	CDD:143165	13/73 (18%)
AgaP_AGAP008943	XP_319698.3	V-set	35..141	CDD:284989	18/62 (29%)
		IG_like	36..123	CDD:214653	13/43 (30%)
		IG_like	153..238	CDD:214653	27/95 (28%)
		Ig	164..235	CDD:143165	21/80 (26%)
		IG_like	248..323	CDD:214653	17/87 (20%)
		Ig_2	256..333	CDD:290606	16/79 (20%)
		I-set	337..423	CDD:254352
		IGc2	351..415	CDD:197706
		FN3	431..520	CDD:238020
		FN3	551..622	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810