DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr1 and AgaP_AGAP011195

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	XP_309446.4	Gene:	AgaP_AGAP011195 / 1270727	VectorBaseID:	AGAP011195	Length:	439	Species:	Anopheles gambiae

Alignment Length:	294	Identity:	70/294 - (23%)
Similarity:	103/294 - (35%)	Gaps:	104/294 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 VGQTGFLHCRVERLGDKDVSWIRKRDLHILTAGGTTYTSDQRFQVLRPDGSANWTLQIKYPQPRD 131
            :|.:..|.|:|:.||...:.|  :|...:|||.....|.|.||:::.     .:.|||...:.:|
Mosquito    18 IGDSIELPCKVKDLGSYVLLW--RRGTSVLTAANLMVTRDPRFKLVE-----GYNLQIANVKIQD 75

  Fly   132 SGVYECQINTEPKMSLSYTFNVVELKAEIFGPSDLMV---------KTGSDINLTCKIMQGPHEL 187
            :|.|.|||.........:|.       ||..|..:.|         :.||.:.|.||....|  :
Mosquito    76 AGDYICQIGDNESRDQVHTL-------EILVPPTIRVVPQNRQITARKGSTVTLECKASGNP--V 131

  Fly   188 GNIFWYK-----GSEML------------------------DGKGEN---EIDSSMAR---IRVE 217
            ..|:|:|     ||..|                        :|..|:   :||.::..   |.||
Mosquito   132 PAIYWHKKDAFSGSSHLSESPTLLLERVDRHHAGVYQCTADNGVRESVHVDIDVTVLSPPDITVE 196

  Fly   218 DDW----------------------------------TD--GLTSR-----LKIKRAMPGDTGNY 241
            ..|                                  ||  .:.||     |.|:.....|.|||
Mosquito   197 KTWVHASEGFDIDLVCIVHGDVNSEMLWYQNSFLLDPTDRRSMYSRGDKYTLNIRNFQQSDFGNY 261

  Fly   242 TCVP--TVAKTSSVYVHVIIGEHPAAMQHNSSSN 273
            :||.  .:.:|.. |:.|.....|||.|..:.||
Mosquito   262 SCVADNALGRTKK-YIEVSGRPGPAAFQSPAYSN 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	25/86 (29%)
		IG_like	60..150	CDD:214653	24/82 (29%)
		IG_like	163..257	CDD:214653	36/180 (20%)
		Ig	174..244	CDD:143165	28/145 (19%)
AgaP_AGAP011195	XP_309446.4	IG_like	19..99	CDD:214653	27/93 (29%)
		Ig	22..83	CDD:143165	21/67 (31%)
		Ig	66..>128	CDD:299845	19/68 (28%)
		IG_like	110..187	CDD:214653	16/78 (21%)
		IGc2	117..175	CDD:197706	12/59 (20%)
		IG_like	199..279	CDD:214653	15/80 (19%)
		Ig	210..277	CDD:143165	14/67 (21%)
		FN3	<353..388	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810