DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr1 and ncam2

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_571905.1	Gene:	ncam2 / 114441	ZFINID:	ZDB-GENE-010822-1	Length:	795	Species:	Danio rerio

Alignment Length:	324	Identity:	68/324 - (20%)
Similarity:	109/324 - (33%)	Gaps:	91/324 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 PPTTSTTTISPSNLLPYFDFDVPRNLTVTVGQTGFLHCRVERLGDKDVSWIRKRDLHILTAGGTT 102
            ||..|         :|...|    |.|...|::....||.....:.||:|.||         |..
Zfish   206 PPVVS---------VPQQSF----NATADYGESVTFTCRAYGSPEPDVTWHRK---------GVQ 248

  Fly   103 YTSDQRFQVLRPDGSANWTLQIKYPQPRDSGVYECQINTEPKMSLSYTFNVVELKAEIFGPSDLM 167
            ....:|: |:|..|:   ||.::..|..|.|.|.|:.:.:........|..|.::..|....::.
Zfish   249 LQESERY-VMRARGT---TLTVRNIQQDDGGSYTCRASNKAGEVEHELFLKVFVQPHITKLRNVT 309

  Fly   168 VKTGSDINLTCKIMQGPHELGNIFWYKGSEMLDGKGENEIDSSM-ARIRVEDDWTDGLTSRLKIK 231
            ...||...::||....|  |..|.|.:.|   ||...::.|.|. .|:.|...:.:.:.:.:.:|
Zfish   310 AVEGSAAMISCKAEGEP--LPEISWRRAS---DGHSFSDGDKSPDGRVEVRGRYGESMLTIVVVK 369

  Fly   232 RAMPGDTGNYTCVPTVAKTSSVYVHVIIGEHPAAM------QHNSSSNSNSFY------CGICCM 284
            .:   |.|.:.| ..:::         ||.|..:|      .....:|...|:      ..|.|.
Zfish   370 LS---DWGRFDC-EALSR---------IGGHQKSMFLDIEYAPKFQANHTIFFSWEGNPVNISCD 421

  Fly   285 LLSIVSCCLQHFYETGCGYLHAAAALAKSAGLGPP-----KRATLTTSETGISAAEVAAAAGAS 343
            ::|                             .||     :|..||....|.....|..|.|.|
Zfish   422 VMS-----------------------------NPPATMLWRREKLTIPSEGAGNMRVYTAPGRS 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	23/94 (24%)
		IG_like	60..150	CDD:214653	22/89 (25%)
		IG_like	163..257	CDD:214653	19/94 (20%)
		Ig	174..244	CDD:143165	16/70 (23%)
ncam2	NP_571905.1	Ig1_NCAM-2	20..111	CDD:143274
		I-set	21..110	CDD:254352
		IGc2	127..187	CDD:197706
		Ig	213..299	CDD:299845	25/102 (25%)
		I-set	213..296	CDD:254352	24/99 (24%)
		Ig	298..395	CDD:299845	24/114 (21%)
		I-set	300..393	CDD:254352	24/110 (22%)
		IG_like	411..488	CDD:214653	13/75 (17%)
		IGc2	412..480	CDD:197706	13/74 (18%)
		FN3	494..586	CDD:238020
		fn3	<616..675	CDD:278470
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910