DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr1 and SPEGNB

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_001273740.1	Gene:	SPEGNB / 100996693	HGNCID:	51251	Length:	238	Species:	Homo sapiens

Alignment Length:	206	Identity:	53/206 - (25%)
Similarity:	83/206 - (40%)	Gaps:	45/206 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 RNLTVTVGQTGFLHCRVERLGDKDVSWIRK----RDLHILTAGGTTYTSDQRFQVLRPDGSANWT 121
            :::.:..|....|.||:....|..:.|.:.    ||       |..|    |:....||..|
Human    61 KDVVLIEGSAAKLTCRISAFPDPFIRWSKDGKELRD-------GPKY----RYVFEDPDVVA--- 111

  Fly   122 LQIKYPQPRDSGVYECQINTEPKMSLSYTFNV-VELKAEI-FGPSDLMVKTGSDINLTCKIMQGP 184
            |.::..:..|.|.|...: |.|....|.:..: ||:..:| .||.:...:.|:.:.||.:|:..|
Human   112 LVVRDGELADLGQYSINV-TNPFGQCSDSARILVEVPTKIQKGPDNTKARKGTTVTLTAEILGEP 175

  Fly   185 HELGNIFWYKGSEMLDGKGENEIDSSMARIRVEDDWTDGLTSRLKIKRAMPGDTGNYTCVPTVAK 249
              ..::.|.|     ||:...|.|    |:..|...|   |:.|.|:||.|.|:|.|
Human   176 --APDVGWTK-----DGEDIEEDD----RVFFEIGST---TTTLTIRRATPQDSGKY-------- 218

  Fly   250 TSSVYVHVIIG 260
              .|||...:|
Human   219 --EVYVENSLG 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	21/97 (22%)
		IG_like	60..150	CDD:214653	21/92 (23%)
		IG_like	163..257	CDD:214653	27/93 (29%)
		Ig	174..244	CDD:143165	22/69 (32%)
SPEGNB	NP_001273740.1	IQ	27..49	CDD:197470
		I-set	54..144	CDD:369462	21/97 (22%)
		I-set	149..237	CDD:369462	30/103 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910