DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr1 and cadm1

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	XP_004916145.1	Gene:	cadm1 / 100496522	XenbaseID:	XB-GENE-6033349	Length:	457	Species:	Xenopus tropicalis

Alignment Length:	348	Identity:	74/348 - (21%)
Similarity:	114/348 - (32%)	Gaps:	122/348 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 VPRNLTVTVGQTGFLHCRVERLGDKDVSWIRK-------RDLHILTAGGTTYTSDQRFQVLRPDG 116
            |..::||..|:...:.|||:...|..:..:..       ||:..|        .|.|||::....
Frog    55 VTEDVTVVEGEVAIISCRVKNSDDSVIQLLNPNRQTIYFRDVRPL--------KDSRFQLVNFSS 111

  Fly   117 S------ANWTLQIKYPQPRDSGVYECQINTEPKMSLSYTFNVVELKAEIFGPSDLMVKT----- 170
            :      :|.||:       |.|.|.||:.|:|......|..|      :..|.:|::..
Frog   112 NELRVSLSNVTLE-------DEGRYLCQVYTDPPQEAFTTITV------LVPPHNLVIDVQKDTY 163

  Fly   171 --GSDINLTCKIMQGPHELGNIFWYKGSEMLDG-KGENE-IDSSMARIRV--------EDD---- 219
              |.::.:.|..: .......|.|:||::.|.. |.:.| ::..|.|:|.        |||
Frog   164 VEGEEVEMNCTAL-ASKPAAAIRWFKGNKELTAVKTDVEPMEERMFRVRSQLVLTAKREDDGIPI 227

  Fly   220 -------------------------------WTDGLTSRLKIKRAMPGDTGNYTCVPTVAKTSSV 253
                                           :..|||..        |:|....|..| .|.|..
Frog   228 VCLVDHPAVKDLQTQQYLEVQYKPLVSVSVKYPQGLTRE--------GETLELVCSAT-GKPSPE 283

  Fly   254 YV-----------HV-IIGEHPAAMQHNSSSNSNSFYCGICCMLLSIVSCCLQHFYETGCGYLHA 306
            .|           || |:|::  .:..|.:...|..|  .|....|:.|....:   |...|.|.
Frog   284 RVLWQRVDDDLPEHVLILGDN--LLFGNLNKTDNGTY--RCEASNSVGSASADY---TLFVYDHP 341

  Fly   307 AAALAKSAGLGPPKRATLTTSET 329
            ..       |.||...|.||:.|
Frog   342 TT-------LPPPTTTTTTTTTT 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	26/107 (24%)
		IG_like	60..150	CDD:214653	24/102 (24%)
		IG_like	163..257	CDD:214653	27/156 (17%)
		Ig	174..244	CDD:143165	19/114 (17%)
cadm1	XP_004916145.1	Ig1_Necl-2	53..147	CDD:143289	26/106 (25%)
		Ig2_Necl-2	168..250	CDD:143291	14/82 (17%)
		IGc2	266..327	CDD:197706	16/73 (22%)
		4.1m	410..428	CDD:128590
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	82	1.000	Inparanoid score	I5030
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050