DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr1 and hmcn2

DIOPT Version :9

Sequence 1:NP_001286645.1 Gene:dpr1 / 2768858 FlyBaseID:FBgn0040726 Length:367 Species:Drosophila melanogaster
Sequence 2:XP_031747766.1 Gene:hmcn2 / 100490941 XenbaseID:XB-GENE-6034990 Length:4625 Species:Xenopus tropicalis


Alignment Length:350 Identity:83/350 - (23%)
Similarity:126/350 - (36%) Gaps:118/350 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 GY---NAALAPTPPTTSTTTISPSNLLPYFDFDVPRNLTVTVGQTGFLHCRVERLGD--KDVSWI 88
            ||   ..::|..|||.:.|                .|:|..||.:..|.|.|  ||:  .:::|.
 Frog   495 GYARTKVSVADPPPTLAVT----------------HNITTFVGGSAILSCEV--LGEIRYNLTWA 541

  Fly    89 RKRDLHILTAGGTTYTSDQRFQVLRPDGSANWTLQIKYPQPRDSGVYECQINTE---PKMSLSYT 150
            .         .|..: .:.|.::|     ||.:|:|...|..|:|.|:|..:.:   ...||..|
 Frog   542 H---------SGKAF-REGRVRIL-----ANSSLEILNAQASDAGEYQCTASNDHGATTASLWLT 591

  Fly   151 FNV---VELKAEIFGPSDLMVKTGSDINLTCKIMQGPHELGNIFWYKGSEMLDGKGENEIDSSMA 212
            ...   :|:|:     |.:.:..|.::.|.|.:...|  :..:.|         |.|:...|:.:
 Frog   592 IQAPPSIEIKS-----SSMQLSHGEEVTLRCDVSGNP--VPQVSW---------KHEDSFLSNGS 640

  Fly   213 RIRVEDDWTDGLTSRLKIKRAMPGDTGNYTCVPTVA-KTSSVYVHVIIGEHPAAMQHNSSSNSNS 276
            |..|.|:      |.|.||.|...|.|||:||.:.: .|....|.:...|.|.|           
 Frog   641 RYTVLDN------STLLIKDAGQEDAGNYSCVASNSLGTDEQTVFLTYVERPKA----------- 688

  Fly   277 FYCGICCMLL------SIVSCCLQHFYETGCGYLHAAAALAKSAGLGPP--------KRATLTTS 327
              ..:..::|      :|:.|.                    |.||.||        |..|.|.|
 Frog   689 --TAVKALVLVPLGEDAILECL--------------------SEGLPPPVVTWYKDDKEVTGTES 731

  Fly   328 ETG---ISAAEVAAAAGAS-AAVAS 348
            .|.   :...||.|..|.. |.|||
 Frog   732 GTNGGTLKLQEVRAEDGGKYACVAS 756

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr1NP_001286645.1 Ig 59..154 CDD:299845 25/102 (25%)
IG_like 60..150 CDD:214653 24/94 (26%)
IG_like 163..257 CDD:214653 25/94 (27%)
Ig 174..244 CDD:143165 19/69 (28%)
hmcn2XP_031747766.1 vWFA 29..165 CDD:238119
IG_like 434..503 CDD:214653 2/7 (29%)
Ig strand B 434..438 CDD:409353
Ig strand C 447..451 CDD:409353
Ig strand E 469..473 CDD:409353
Ig strand F 483..488 CDD:409353
Ig 514..592 CDD:416386 24/94 (26%)
Ig strand A' 515..518 CDD:409353 1/2 (50%)
Ig strand B 524..531 CDD:409353 3/8 (38%)
Ig strand C 537..542 CDD:409353 1/4 (25%)
Ig strand C' 544..546 CDD:409353 1/1 (100%)
Ig strand D 551..555 CDD:409353 1/3 (33%)
Ig strand E 558..563 CDD:409353 1/4 (25%)
Ig strand F 571..579 CDD:409353 3/7 (43%)
Ig strand G 582..592 CDD:409353 2/9 (22%)
I-set 596..681 CDD:400151 27/106 (25%)
Ig strand B 613..617 CDD:409353 1/3 (33%)
Ig strand C 626..630 CDD:409353 1/12 (8%)
Ig strand E 648..652 CDD:409353 2/3 (67%)
Ig strand F 662..667 CDD:409353 3/4 (75%)
Ig strand G 676..679 CDD:409353 0/2 (0%)
Ig 695..770 CDD:416386 20/81 (25%)
Ig strand B 703..707 CDD:409353 1/3 (33%)
Ig strand C 716..720 CDD:409353 0/3 (0%)
Ig strand E 736..740 CDD:409353 0/3 (0%)
Ig strand F 750..755 CDD:409353 1/4 (25%)
Ig strand G 763..766 CDD:409353
Ig strand A 774..778 CDD:409353
IG_like 780..864 CDD:214653
Ig strand A' 781..786 CDD:409353
Ig strand B 790..798 CDD:409353
Ig strand C 804..809 CDD:409353
Ig strand C' 812..815 CDD:409353
Ig strand D 822..825 CDD:409353
Ig strand F 843..851 CDD:409353
I-set 870..957 CDD:400151
Ig strand A' 878..881 CDD:409353
Ig strand B 887..895 CDD:409353
Ig strand C 901..906 CDD:409353
Ig strand C' 909..911 CDD:409353
Ig strand D 917..921 CDD:409353
Ig strand E 923..927 CDD:409353
Ig strand F 936..944 CDD:409353
Ig strand G 947..957 CDD:409353
I-set 961..1048 CDD:400151
Ig strand A' 969..973 CDD:409353
Ig strand B 977..984 CDD:409353
Ig strand C 991..996 CDD:409353
Ig strand C' 998..1001 CDD:409353
Ig strand D 1007..1011 CDD:409353
Ig strand E 1014..1020 CDD:409353
Ig strand F 1027..1035 CDD:409353
Ig strand G 1038..1048 CDD:409353
Ig 1065..1146 CDD:416386
Ig strand A' 1067..1070 CDD:409353
Ig strand B 1076..1083 CDD:409353
Ig strand C 1089..1094 CDD:409353
Ig strand C' 1096..1098 CDD:409353
Ig strand D 1105..1109 CDD:409353
Ig strand E 1112..1117 CDD:409353
Ig strand F 1125..1133 CDD:409353
Ig strand G 1136..1146 CDD:409353
Ig 1157..1237 CDD:416386
Ig strand B 1167..1174 CDD:409353
Ig strand C 1180..1185 CDD:409353
Ig strand C' 1187..1189 CDD:409353
Ig strand D 1196..1200 CDD:409353
Ig strand E 1203..1208 CDD:409353
Ig strand F 1216..1224 CDD:409353
Ig strand G 1227..1237 CDD:409353
Ig 1241..1329 CDD:416386
Ig strand A 1241..1244 CDD:409353
Ig strand A' 1250..1253 CDD:409353
Ig strand B 1259..1266 CDD:409353
Ig strand C 1272..1277 CDD:409353
Ig strand C' 1280..1282 CDD:409353
Ig strand D 1289..1293 CDD:409353
Ig strand E 1295..1299 CDD:409353
Ig strand F 1308..1316 CDD:409353
Ig strand G 1319..1329 CDD:409353
I-set 1342..1420 CDD:400151
Ig strand A' 1343..1346 CDD:409353
Ig strand B 1352..1359 CDD:409353
Ig strand C 1365..1370 CDD:409353
Ig strand C' 1373..1375 CDD:409353
Ig strand D 1381..1385 CDD:409353
Ig strand E 1387..1392 CDD:409353
Ig strand F 1401..1409 CDD:409353
Ig strand G 1412..1420 CDD:409353
I-set 1434..1516 CDD:400151
Ig strand A' 1436..1439 CDD:409353
Ig strand B 1445..1452 CDD:409353
Ig strand C 1458..1463 CDD:409353
Ig strand C' 1465..1467 CDD:409353
Ig strand D 1474..1478 CDD:409353
Ig strand E 1481..1487 CDD:409353
Ig strand F 1495..1503 CDD:409353
I-set 1538..1609 CDD:400151
Ig strand B 1539..1546 CDD:409353
Ig strand C 1552..1557 CDD:409353
Ig strand C' 1559..1561 CDD:409353
Ig strand D 1567..1571 CDD:409353
Ig strand E 1574..1580 CDD:409353
Ig strand F 1588..1596 CDD:409353
Ig strand G 1599..1609 CDD:409353
Ig 1621..1703 CDD:416386
Ig strand A' 1624..1628 CDD:409353
Ig strand B 1632..1639 CDD:409353
Ig strand C 1646..1651 CDD:409353
Ig strand C' 1653..1656 CDD:409353
Ig strand D 1661..1665 CDD:409353
Ig strand E 1668..1675 CDD:409353
Ig strand F 1682..1690 CDD:409353
I-set 1717..1796 CDD:400151
Ig strand C 1739..1743 CDD:409353
Ig strand E 1762..1766 CDD:409353
Ig strand F 1776..1781 CDD:409353
Ig 1796..1880 CDD:416386
Ig strand A' 1801..1804 CDD:409353
Ig strand B 1818..1825 CDD:409353
Ig strand C 1831..1836 CDD:409353
Ig strand C' 1838..1840 CDD:409353
Ig strand F 1859..1867 CDD:409353
Ig strand G 1870..1880 CDD:409353
I-set 1886..1964 CDD:400151
Ig strand A' 1892..1895 CDD:409353
Ig strand B 1901..1908 CDD:409353
Ig strand C 1914..1919 CDD:409353
Ig strand C' 1920..1922 CDD:409353
Ig strand D 1929..1933 CDD:409353
Ig strand E 1936..1942 CDD:409353
Ig strand F 1950..1958 CDD:409353
Ig 1984..2063 CDD:416386
Ig strand B 1992..1999 CDD:409353
Ig strand C 2005..2010 CDD:409353
Ig strand C' 2012..2014 CDD:409353
Ig strand D 2022..2025 CDD:409353
Ig strand E 2029..2035 CDD:409353
Ig strand F 2042..2049 CDD:409353
Ig strand G 2055..2063 CDD:409353
Ig_3 2066..2141 CDD:404760
Ig strand B 2084..2088 CDD:409353
Ig strand C 2097..2101 CDD:409353
Ig strand E 2120..2124 CDD:409353
Ig strand F 2134..2139 CDD:409353
Ig strand A 2158..2161 CDD:409353
Ig strand A' 2167..2170 CDD:409353
Ig 2170..2246 CDD:416386
Ig strand B 2176..2183 CDD:409353
Ig strand C 2189..2194 CDD:409353
Ig strand C' 2197..2199 CDD:409353
Ig strand E 2204..2216 CDD:409353
Ig strand F 2225..2233 CDD:409353
Ig strand G 2236..2246 CDD:409353
I-set 2259..2340 CDD:400151
Ig strand B 2270..2274 CDD:409353
Ig strand C 2283..2287 CDD:409353
Ig strand E 2306..2310 CDD:409353
Ig strand F 2320..2325 CDD:409353
Ig_3 2343..2421 CDD:404760
Ig strand B 2364..2368 CDD:409353
Ig strand C 2377..2381 CDD:409353
Ig strand E 2400..2404 CDD:409353
Ig strand F 2414..2419 CDD:409353
Ig strand A 2437..2440 CDD:409353
I-set 2447..2526 CDD:400151
Ig strand A' 2447..2450 CDD:409353
Ig strand B 2455..2463 CDD:409353
Ig strand C 2469..2473 CDD:409353
Ig strand C' 2476..2479 CDD:409353
Ig strand D 2484..2488 CDD:409353
Ig strand E 2492..2497 CDD:409353
Ig strand F 2505..2513 CDD:409353
Ig strand G 2516..2526 CDD:409353
I-set 2530..2622 CDD:400151
Ig strand B 2552..2556 CDD:409353
Ig strand C 2565..2569 CDD:409353
Ig strand E 2588..2592 CDD:409353
Ig strand F 2602..2607 CDD:409353
I-set 2633..2720 CDD:400151
Ig strand B 2650..2654 CDD:409353
Ig strand C 2663..2667 CDD:409353
Ig strand E 2686..2690 CDD:409353
Ig strand F 2700..2705 CDD:409353
Ig 2760..2830 CDD:416386
Ig strand B 2760..2764 CDD:409353
Ig strand C 2773..2777 CDD:409353
Ig strand E 2797..2800 CDD:409353
Ig strand F 2810..2815 CDD:409353
I-set 2839..2925 CDD:400151
Ig strand A' 2845..2850 CDD:409353
Ig strand B 2855..2863 CDD:409353
Ig strand C 2867..2873 CDD:409353
Ig strand C' 2875..2877 CDD:409353
Ig strand D 2883..2889 CDD:409353
Ig strand E 2890..2896 CDD:409353
Ig strand F 2905..2912 CDD:409353
Ig strand G 2915..2923 CDD:409353
I-set 2929..3017 CDD:400151
Ig strand A 2929..2932 CDD:409353
Ig strand A' 2936..2941 CDD:409353
Ig strand B 2947..2954 CDD:409353
Ig strand C 2960..2965 CDD:409353
Ig strand D 2976..2979 CDD:409353
Ig strand E 2983..2989 CDD:409353
Ig strand F 2996..3003 CDD:409353
Ig strand G 3009..3017 CDD:409353
Ig strand A 3020..3029 CDD:409353
I-set 3034..3111 CDD:400151
Ig strand B 3039..3049 CDD:409353
Ig strand C 3053..3059 CDD:409353
Ig strand C' 3061..3064 CDD:409353
Ig strand E 3077..3083 CDD:409353
Ig strand F 3089..3098 CDD:409353
Ig_3 3116..3189 CDD:404760
Ig strand A 3119..3122 CDD:409353
Ig strand A' 3124..3128 CDD:409353
Ig strand B 3132..3139 CDD:409353
Ig strand C 3146..3151 CDD:409353
Ig strand C' 3153..3156 CDD:409353
Ig strand D 3162..3166 CDD:409353
Ig strand E 3168..3174 CDD:409353
Ig strand F 3181..3189 CDD:409353
Ig_3 3206..3284 CDD:404760
Ig strand B 3225..3229 CDD:409353
Ig strand C 3238..3242 CDD:409353
Ig strand E 3263..3267 CDD:409353
Ig strand F 3277..3282 CDD:409353
Ig strand G 3291..3294 CDD:409353
I-set 3318..3391 CDD:400151
Ig strand B 3321..3325 CDD:409353
Ig strand C 3334..3338 CDD:409353
Ig strand E 3357..3361 CDD:409353
Ig strand F 3371..3376 CDD:409353
Ig strand A 3395..3398 CDD:409353
Ig strand A' 3403..3408 CDD:409353
I-set 3406..3484 CDD:400151
Ig strand B 3414..3421 CDD:409353
Ig strand C 3427..3432 CDD:409353
Ig strand D 3443..3446 CDD:409353
Ig strand E 3450..3456 CDD:409353
Ig strand F 3463..3470 CDD:409353
Ig strand G 3476..3484 CDD:409353
Ig_3 3487..3561 CDD:404760
Ig strand A' 3498..3501 CDD:409353
Ig strand B 3507..3514 CDD:409353
Ig strand C 3520..3525 CDD:409353
Ig strand C' 3527..3529 CDD:409353
Ig strand D 3534..3538 CDD:409353
Ig strand E 3541..3546 CDD:409353
Ig strand F 3554..3562 CDD:409353
I-set 3585..3668 CDD:400151
Ig strand A' 3589..3592 CDD:409353
Ig strand B 3598..3605 CDD:409353
Ig strand C 3611..3616 CDD:409353
Ig strand C' 3618..3620 CDD:409353
Ig strand D 3626..3630 CDD:409353
Ig strand E 3633..3639 CDD:409353
Ig strand F 3647..3655 CDD:409353
Ig strand G 3658..3668 CDD:409353
I-set 3672..3759 CDD:400151
Ig strand A 3673..3676 CDD:409353
Ig strand A' 3680..3683 CDD:409353
Ig strand B 3689..3696 CDD:409353
Ig strand C 3702..3707 CDD:409353
Ig strand C' 3709..3711 CDD:409353
Ig strand D 3718..3722 CDD:409353
Ig strand E 3725..3730 CDD:409353
Ig strand F 3738..3746 CDD:409353
TSP1 3766..3817 CDD:214559
TSP1 3822..3873 CDD:214559
nidG2 3876..4057 CDD:412205
EGF_CA 4111..4149 CDD:214542
EGF_CA 4151..4194 CDD:311536
EGF_CA 4196..4233 CDD:214542
EGF_CA 4234..4267 CDD:214542
EGF_CA 4276..4317 CDD:311536
EGF_CA 4319..4358 CDD:311536
EGF_CA 4424..4463 CDD:214542
EGF_CA 4464..4504 CDD:214542
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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