Protein Alignment mei-W68 and rec12

DIOPT Version :9

• Sequence 1: NP_995901.1
• Gene: mei-W68 / 2768853
• FlyBaseID: FBgn0002716
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: NP_593479.1
• Gene: rec12 / 2542150
• PomBaseID: SPAC17A5.11
• Length: 345
• Species: Schizosaccharomyces pombe
• Alignment Length: 351
• Identity: 92/351 - (26%)
• Similarity: 158/351 - (45%)
• Gaps: 50/351 - (14%)

  Fly     5 SENIERIALELLSNLVHGNA-TLSVPRNSSGNVISEYRRVSYNN-RGSRHS-------------- 53
            |.:.:::....:...||... .||.|...|.||..:.|:  :|: .||..|
pombe     3 SNDKKKVVRSWIEQFVHDFVEQLSKPTKDSVNVALKRRK--HNSWNGSLDSKANERQKVKVFSFP 65

  Fly    54 -----FCVLIYMLSRVHRLQVRGGSFTVRGLYYDNPLLVRSQSRIAEARLDVCRMLRTSPLSLGI 113
                 ...|..:|..||...:.....|.|.:||.:..|.:.|:.:.|...|:...:..|...|.:
pombe    66 RNETTIAQLFRVLDCVHEAVISDTVITKRDIYYRDVDLFKRQTVVDELLGDISNTIGCSRSDLNV 130

  Fly   114 LAASKGLVAGDLRLLMTNGDVLDSSLYGGPLTLPTDPEKIDRIETLAEFVLIVEKESVFESLLSR 178
            .|::||||.|.:.:.:.||.|:.::   .||.:  ...:|..|.:.|::||::|||:||::|...
pombe   131 EASAKGLVFGSIHIALENGTVITAT---KPLLI--SHHRISSITSTAKWVLVIEKEAVFQTLTEE 190

  Fly   179 NVFGTFERRFILITGKGYPDCCTRRIVHRLTEENQLAAYI-LVDADPFGVEIMLVYRHGSKSMSF 242
            .:..|     |::|.||:||..||:.:.:|.:....|.:. :.|.||.|:.|...:::||.:.|.
pombe   191 ALADT-----IIVTAKGFPDLMTRKFLVKLAKALPDAKFFGIFDWDPHGLCIYSCFKYGSNAYSH 250

  Fly   243 SSQG------LTTPALRWIGLHPSEIPALGTGAVALVAGDNKKINDLLARHDL--EPGVRQELRM 299
            ....      |..|....|.....|.      ::.|...|.|.|..||.....  ||.||::|:.
pombe   251 EPHSQLRNLQLLGPLYEDIFNKNQEF------SLKLNKRDIKMITTLLQFEGFQKEPVVREQLQR 309

  Fly   300 LQDVQLKAEIESVIDFLTDDYIPNKI 325
            :..:|.||||:::::|  ..:|..|:
pombe   310 MLFIQKKAEIQAILEF--PSWIKGKL 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mei-W68	NP_995901.1	Spo11	3..327	CDD:224611	92/351 (26%)
		TP6A_N	50..113	CDD:282286	16/81 (20%)
		TOPRIM_TopoIIB_SPO	161..315	CDD:173774	47/162 (29%)
rec12	NP_593479.1	Spo11	1..343	CDD:224611	92/351 (26%)
		TP6A_N	69..130	CDD:282286	14/60 (23%)
		TOPRIM_TopoIIB_SPO	173..328	CDD:173774	48/167 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	77	1.000	Domainoid score	I2433
eggNOG	1	0.900	-	-		E1_COG1697
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	94	1.000	Inparanoid score	I1718
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002859
OrthoInspector	1	1.000	-	-		oto101104
orthoMCL	1	0.900	-	-		OOG6_101269
Panther	1	1.100	-	-	LDO	PTHR10848
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1077
SonicParanoid	1	1.000	-	-		X2691
TreeFam	1	0.960	-	-
	12	11.850