DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment par-1 and SIP3

DIOPT Version :9

Sequence 1:	NP_995894.2	Gene:	par-1 / 2768852	FlyBaseID:	FBgn0260934	Length:	1170	Species:	Drosophila melanogaster
Sequence 2:	NP_194825.1	Gene:	SIP3 / 829221	AraportID:	AT4G30960	Length:	441	Species:	Arabidopsis thaliana

Alignment Length:	356	Identity:	129/356 - (36%)
Similarity:	200/356 - (56%)	Gaps:	21/356 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   251 GKYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQ-LNPGSLQKLFREVRIMKMLDHPNIVK 314
            |:|:|.:.:|.|.||||..|:::.|||.||:|::.|.: :..|.:.::.||:.:|:|:.|||||:
plant    22 GRYELGRLLGHGTFAKVYHARNIQTGKSVAMKVVGKEKVVKVGMVDQIKREISVMRMVKHPNIVE 86

  Fly   315 LFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAE 379
            |.:|:.::..:|..||...|||:| ..|..||::|..|||.|:|::|||.:||.:.:.|||||.|
plant    87 LHEVMASKSKIYFAMELVRGGELF-AKVAKGRLREDVARVYFQQLISAVDFCHSRGVYHRDLKPE 150

  Fly   380 NLLLDSELNIKIADFGFSNEFTPGSKLD----TFCGSPPYAAPELFQGKKYDGPEVDVWSLGVIL 440
            |||||.|.|:|:.|||.| .||...|.|    |.||:|.|.|||:...|.|||.:.|:||.||||
plant   151 NLLLDEEGNLKVTDFGLS-AFTEHLKQDGLLHTTCGTPAYVAPEVILKKGYDGAKADLWSCGVIL 214

  Fly   441 YTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWMN 505
            :.|::|.|||....|..:..::.||.::.|.::|:|...|:.|.|..||..|.::|.:|...|
plant   215 FVLLAGYLPFQDDNLVNMYRKIYRGDFKCPGWLSSDARRLVTKLLDPNPNTRITIEKVMDSPW-- 277

  Fly   506 MGFEEDELKPYIEPKAD--LADPKRIEALVAMGYNRSEIEASLSQVRYDDVFATYLLLGRKSTDP 568
              |::...:...||.|.  ....:.::.||......:|...:...:...:.|....|...|..:.
plant   278 --FKKQATRSRNEPVAATITTTEEDVDFLVHKSKEETETLNAFHIIALSEGFDLSPLFEEKKKEE 340

  Fly   569 ESD----GSRSGSSLSLRNISGNDAGANAGS 595
            :.:    .||..||:    ||..:..|..|:
plant   341 KREMRFATSRPASSV----ISSLEEAARVGN 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	109/256 (43%)
		S_TKc	253..504	CDD:214567	109/255 (43%)
		UBA_MARK_Par1	525..563	CDD:270522	5/37 (14%)
		MARK1-3_C	839..936	CDD:213381
SIP3	NP_194825.1	PKc_like	23..277	CDD:419665	109/255 (43%)
SIP3	NP_194825.1	CIPK_C	316..432	CDD:213380	11/56 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910