DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment par-1 and CIPK8

DIOPT Version :9

Sequence 1:	NP_995894.2	Gene:	par-1 / 2768852	FlyBaseID:	FBgn0260934	Length:	1170	Species:	Drosophila melanogaster
Sequence 2:	NP_194171.1	Gene:	CIPK8 / 828542	AraportID:	AT4G24400	Length:	445	Species:	Arabidopsis thaliana

Alignment Length:	339	Identity:	131/339 - (38%)
Similarity:	192/339 - (56%)	Gaps:	44/339 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   250 IGKYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDK-TQLNPGSLQKLFREVRIMKMLDHPNIV 313
            :|||:|.:|||:|.|||||.|::..||:.||:||:|: |.:....:.::.||:.|||::.||.:|
plant     6 VGKYELGRTIGEGTFAKVKFAQNTETGESVAMKIVDRSTIIKRKMVDQIKREISIMKLVRHPCVV 70

  Fly   314 KLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLKA 378
            :|::|:.:...:|:|:||.:|||:||.:|.:||:.|.|||..|.|::..|.|||.|.:.|||||.
plant    71 RLYEVLASRTKIYIILEYITGGELFDKIVRNGRLSESEARKYFHQLIDGVDYCHSKGVYHRDLKP 135

  Fly   379 ENLLLDSELNIKIADFGFSNEFTPG-SKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYT 442
            |||||||:.|:||:|||.|.....| :.|.|.||:|.|.|||:...|.|:|...|:||.|||||.
plant   136 ENLLLDSQGNLKISDFGLSALPEQGVTILKTTCGTPNYVAPEVLSHKGYNGAVADIWSCGVILYV 200

  Fly   443 LVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWMNMG 507
            |::|.||||...|..|..::.:.::..|.|.:...::|:.:.|..||..|.::..|..|:|.
plant   201 LMAGYLPFDEMDLPTLYSKIDKAEFSCPSYFALGAKSLINRILDPNPETRITIAEIRKDEWF--- 262

  Fly   508 FEEDELKPYIEPKADLADPKRIEALVAMGYNRSEIEASLSQVRYDDVFATYLLLGRKSTDPE--- 569
                 ||.|  ....|.|                    ...|..|||:|.:       .|||
plant   263 -----LKDY--TPVQLID--------------------YEHVNLDDVYAAF-------DDPEEQT 293

  Fly   570 --SDGSRSGSSLSL 581
              .||:|....|:|
plant   294 YAQDGTRDTGPLTL 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	111/253 (44%)
		S_TKc	253..504	CDD:214567	110/252 (44%)
		UBA_MARK_Par1	525..563	CDD:270522	6/37 (16%)
		MARK1-3_C	839..936	CDD:213381
CIPK8	NP_194171.1	PKc_like	8..261	CDD:419665	111/252 (44%)
CIPK8	NP_194171.1	CIPK_C	308..423	CDD:213380	131/339 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910