DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment par-1 and KIN11

DIOPT Version :9

Sequence 1:	NP_995894.2	Gene:	par-1 / 2768852	FlyBaseID:	FBgn0260934	Length:	1170	Species:	Drosophila melanogaster
Sequence 2:	NP_566843.1	Gene:	KIN11 / 822566	AraportID:	AT3G29160	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	395	Identity:	158/395 - (40%)
Similarity:	236/395 - (59%)	Gaps:	38/395 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   247 EEHIGKYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHP 310
            |..:..|||.||:|.|:|.|||:|:|:.||.:|||||:::.:: |....:|:.||::|:::..||
plant    14 ESILPNYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHP 78

  Fly   311 NIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHRD 375
            :|::.::||||...:|::|||...||:|||:|..||::|.|||..|:||:|.|:|||:..::|||
plant    79 HIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRNMVVHRD 143

  Fly   376 LKAENLLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVIL 440
            ||.|||||||..||||||||.||....|..|.|.||||.|||||:..||.|.||||||||.||||
plant   144 LKPENLLLDSRCNIKIADFGLSNVMRDGHFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVIL 208

  Fly   441 YTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWMN 505
            |.|:.|:||||...:..|.:::..|.|.:|.::|::..:|:.:.|:::|.||.::..|...:|.
plant   209 YALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSSEARDLIPRMLIVDPVKRITIPEIRQHRWF- 272

  Fly   506 MGFEEDELKPY--IEPKADLADPKRI-----EALVAMGYNRSEIEASLSQVRYDDVFAT-YLLLG 562
                :..|..|  :.|...:...|:|     :.:|.||::|:::..||.....:|...| ||||.
plant   273 ----QTHLPRYLAVSPPDTVEQAKKINEEIVQEVVNMGFDRNQVLESLRNRTQNDATVTYYLLLD 333

  Fly   563 RKSTDP----ESDGSRSGSSLSLRNISGNDAGAN------AGSASVQS--PTHRGVHRSISASST 615
            .:...|    ||:...:           .|:|:|      ||::.|..  |.|.. |..:.|.|.
plant   334 NRFRVPSGYLESEFQET-----------TDSGSNPMRTPEAGASPVGHWIPAHVD-HYGLGARSQ 386

  Fly   616 KPSRR 620
            .|..|
plant   387 VPVDR 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	123/252 (49%)
		S_TKc	253..504	CDD:214567	123/251 (49%)
		UBA_MARK_Par1	525..563	CDD:270522	14/43 (33%)
		MARK1-3_C	839..936	CDD:213381
KIN11	NP_566843.1	STKc_AMPK_alpha	17..272	CDD:270981	123/254 (48%)
		UBA_SnRK1_plant	294..334	CDD:270520	13/39 (33%)
		AMPKA_C	391..509	CDD:213378	1/1 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910