DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment par-1 and Gm7168

DIOPT Version :9

Sequence 1:	NP_995894.2	Gene:	par-1 / 2768852	FlyBaseID:	FBgn0260934	Length:	1170	Species:	Drosophila melanogaster
Sequence 2:	XP_006524826.1	Gene:	Gm7168 / 635895	MGIID:	3643198	Length:	549	Species:	Mus musculus

Alignment Length:	366	Identity:	140/366 - (38%)
Similarity:	211/366 - (57%)	Gaps:	12/366 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   248 EHIGKYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 312
            |...:||:::|:|.|.:|||.||||..||..||:|::.|   |....|...:|..|||.:.||||
Mouse    64 ELYSQYKVVRTLGHGTYAKVLLAKHWLTGTPVAVKVLLK---NKPCFQPAMKEANIMKKIKHPNI 125

  Fly   313 VKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLK 377
            |.|.||.||:...|||||...|.|:::|:...|.::|.|||..|.||:|||.|||...|:|||||
Mouse   126 VSLLQVFETKTRGYLIMELVEGQELYEYIKSSGHIEEDEARQIFLQILSAVSYCHGLGIVHRDLK 190

  Fly   378 AENLLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYT 442
            .:|:::|.:.:|||.|||.|.:..||..||..||:..:.|||||..|.|||.:.|:|:||||||.
Mouse   191 PDNIMIDDKGSIKIIDFGLSTQVKPGDLLDEHCGAYAFGAPELFLWKSYDGTKSDLWALGVILYY 255

  Fly   443 LVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWMNMG 507
            :|.|.:|||...:.||:.::|.|.|..|..:|.:.::||...:.:||..|.::..:|...|:. |
Mouse   256 MVVGKVPFDSYIIPELQRQILAGVYPAPCGVSNELKDLLSLLMTVNPKYRPTVTEVMKHPWLR-G 319

  Fly   508 FEEDELKPYIEPKADLADPKRIEALVAMGYNRSEIEASLSQVRYDDVFATYLLLGRKSTDPESDG 572
            ..:.....:.||.....||..::|:..:|:...:|..||::.:::::.|.|.||..::...|
Mouse   320 HCKGLTNIHEEPVPVRPDPDIVDAMQYIGFQAKDIRESLTKEKFNEMSAAYYLLEEQALQRE--- 381

  Fly   573 SRSGSSLSLRNISGNDAGANAGSASVQSPTHRGVHRSISAS 613
            .||..:.::..:.......:||.||...     :.||.|||
Mouse   382 VRSTQAPTVSQVKAPFPSMDAGEASCLK-----IKRSGSAS 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	112/251 (45%)
		S_TKc	253..504	CDD:214567	112/250 (45%)
		UBA_MARK_Par1	525..563	CDD:270522	11/37 (30%)
		MARK1-3_C	839..936	CDD:213381
Gm7168	XP_006524826.1	STKc_AMPK-like	68..316	CDD:270905	112/250 (45%)
Gm7168	XP_006524826.1	UBA_MARK_Par1	336..375	CDD:270522	11/38 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0586
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810