Protein Alignment par-1 and Smok3c

DIOPT Version :9

• Sequence 1: NP_995894.2
• Gene: par-1 / 2768852
• FlyBaseID: FBgn0260934
• Length: 1170
• Species: Drosophila melanogaster
• Sequence 2: NP_001297632.1
• Gene: Smok3c / 622486
• MGIID: 3647925
• Length: 504
• Species: Mus musculus
• Alignment Length: 581
• Identity: 166/581 - (28%)
• Similarity: 261/581 - (44%)
• Gaps: 148/581 - (25%)

  Fly   252 KYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGSLQK-------LFREVRIMKMLDH 309
            :|.:::|||.|..|.||||:|..||..||:|          ::||       :..||.::.|.||
Mouse    27 QYVMLETIGHGGCATVKLAQHRLTGTHVAVK----------TIQKRGYWCILIMSEVDLLMMADH 81

  Fly   310 PNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHR 374
            ||::.|.|||||:|.:|||||...|..::.::...|.::|.|||..|:|::||:.|||.:.|:||
Mouse    82 PNVISLLQVIETKKKVYLIMELCEGKSLYQHIRKAGYLQEHEARALFKQLLSAMNYCHNQGIVHR 146

  Fly   375 DLKAENLLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVI 439
            |||.:|::::.:..:||.|||.|.:..||.||:.|||:.|::|||:.....||||::|||:|||:
Mouse   147 DLKPDNIMVEKDGKVKIIDFGLSTKVKPGQKLNLFCGTYPFSAPEVLLSTPYDGPKIDVWTLGVV 211

  Fly   440 LYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWM 504
            ||.:|:|.:|||..:::.|.:|:|.|||.||..:|.:..:||...:..||..|.::..:|...|:
Mouse   212 LYFMVTGKIPFDACSIKRLVKRILAGKYSIPSRLSAELRDLLSLLMTANPKLRPTVAEVMVHPWV 276

  Fly   505 NMGF--------EEDELKPYIEPKADLADPKRIEALVAMGYNRSEIEASLSQVRYDDVFATYLLL 561
            ..|.        |:..|||         ||..::|:..:|:...:||.||.|.:::...|:|.||
Mouse   277 TEGSGVFPDPCEEQTPLKP---------DPAIVKAMGHIGFQAQDIEDSLRQRKFNQTMASYCLL 332

  Fly   562 GRKSTDPESDGSRSGSSLSLRNISGNDAGANAGSASVQSPTHRGVHRSISASSTKPSRRASSGVG 626
             :|....|.|                                            :|:|     ..
Mouse   333 -KKQILKECD--------------------------------------------RPTR-----AR 347

  Fly   627 PTNAAAT-----VAAATGAVGAVNPSNNYNAAGSAADRASVGSNFKRQNTIDSATIKENTARLAA 686
            |.|.:.|     |..||..:|.....|......|:|:|        :.:....:|.|:...|::.
Mouse   348 PVNPSVTPFPSLVDTATTCLGLRRRENEPTCPWSSANR--------QVSVCGKSTSKKRDRRVSW 404

  Fly   687 QN--QRPASATQKMLTTADTTLNSPAKPRTATKYDPTNGNRTVSGTSGIIPRRSTTLYEKTSSTE 749
            .:  .||......|..|...|.:.|..........|.:...:..|            :.:.|:.:
Mouse   405 PSVLGRPRHTAPTMDHTRTRTRSVPCICSMFCTVQPNSSEESTQG------------HTRASAAD 457

  Fly   750 KTNVIPAETNLFDRLRMASAVKSSRHFPRN------------------VPSRSTFHSGQTR 792
            |    |..               ||.:||.                  :||:.|.|.||.|
Mouse   458 K----PVR---------------SRGWPRGIKGWTRMIGNAMRKLCCCIPSKETSHLGQNR 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	106/258 (41%)
		S_TKc	253..504	CDD:214567	106/257 (41%)
		UBA_MARK_Par1	525..563	CDD:270522	13/37 (35%)
		MARK1-3_C	839..936	CDD:213381
Smok3c	NP_001297632.1	STKc_AMPK-like	27..275	CDD:270905	106/257 (41%)
		UBA_MARK_Par1	295..334	CDD:270522	14/48 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0586
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810