Protein Alignment par-1 and mark2

DIOPT Version :9

• Sequence 1: NP_995894.2
• Gene: par-1 / 2768852
• FlyBaseID: FBgn0260934
• Length: 1170
• Species: Drosophila melanogaster
• Sequence 2: XP_012808991.1
• Gene: mark2 / 594939
• XenbaseID: XB-GENE-876451
• Length: 792
• Species: Xenopus tropicalis
• Alignment Length: 831
• Identity: 435/831 - (52%)
• Similarity: 535/831 - (64%)
• Gaps: 124/831 - (14%)

  Fly   188 AINHHHHHTPGSGVAPTVNKNVLSTHSAHPSAI---KQRTSSAKGS-PNMQMRSSAPMRWRATEE 248
            |..|..|  |.|...|.:         ||..|:   .|:|||:..| ||| :|....:...|.|:
 Frog     6 AAKHRDH--PDSCTNPLL---------AHEPALGHADQKTSSSGSSKPNM-LRCRTSIATTADEQ 58

  Fly   249 -HIGKYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 312
             |||.|:|:||||||||||||||:|:.||||||:|||||||||..|||||||||||||:|:||||
 Frog    59 PHIGNYRLLKTIGKGNFAKVKLARHVLTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNI 123

  Fly   313 VKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLK 377
            ||||:||||||||||:||||||||||||||.||||||||||.|||||||||||||||.|:|||||
 Frog   124 VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKLIVHRDLK 188

  Fly   378 AENLLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYT 442
            ||||||||::||||||||||||||.|:||||||||||||||||||||||||||||||||||||||
 Frog   189 AENLLLDSDMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYT 253

  Fly   443 LVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWMNMG 507
            ||||||||||..|:|||||||||||||||||||||||||:|||:||||||.:||.||.|:|||:|
 Frog   254 LVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPAKRGTLEQIMRDRWMNVG 318

  Fly   508 FEEDELKPYIEPKADLADPKRIEALVAMGYNRSEIEASLSQVRYDDVFATYLLLGRKSTDPESDG 572
            .||||||||:||..|..||||.|.::.|||.|.||..||...:|::|.|||||||.||::.::|
 Frog   319 HEEDELKPYVEPIPDYKDPKRTELMITMGYTREEISDSLVNQKYNEVMATYLLLGYKSSETDND- 382

  Fly   573 SRSGSSLSLRNISGNDAGANAGSASVQSPTHRGVHRSISASSTKPSRRASSGVGPTNAAATVAAA 637
                 :|:|:.....|    ..::...||.|: |.||:||:..:  ||.|...||
 Frog   383 -----NLTLKPRPPPD----VTNSIAPSPAHK-VQRSVSANPKQ--RRLSDQAGP---------- 425

  Fly   638 TGAVGAVNPSNNYN---AAGSAADRASVGSNFKRQNTIDSATIKENTARLAAQNQR---PASATQ 696
                 |:..||:|:   .:.:|.:|.|  .:.|......|:|::...:.|:..:::   |..:|.
 Frog   426 -----AIPNSNSYSKKTQSNNAENRRS--EDDKESGRKSSSTVRVPPSPLSGLDRKKTTPTPSTN 483

  Fly   697 KMLTT-ADTTLNSPAKPRTATKYDPTNGNRTVSGTSGIIPRRSTTLYEKTSS-------TEKTNV 753
            .:|:| .:.:.|||...|.:.........:....|.|  .|.||.....||:       :..|:|
 Frog   484 SVLSTGTNRSRNSPMLDRASLVPGSVQNGKDSFSTPG--SRASTASAPATSARIRQHQKSMSTSV 546

  Fly   754 IPAE--------------TNLFDRLRMA--------SAVKSSRHFPRNVPSRSTFHSGQTR-ARN 795
            .|::              :....|:.:|        ||.....:|||.|.||||||:||.| ||:
 Frog   547 HPSKPAPSLDGNCEVQRPSTAPQRVPVASPSAHNISSAATERTNFPRGVSSRSTFHAGQVRQARD 611

  Fly   796 NTALEYSGTSGASGDSSHPGRM----SFFSKLSSRF------------------------SKRP- 831
            ...|.:...|.||...:..||.    |.|||.:|:|                        |.||
 Frog   612 QQNLGFGSVSPASPSGNSQGRRGATGSIFSKFTSKFVRRNLSFRFPRRNPNEPEGKDRVESTRPH 676

  Fly   832 -TIADEA--------AKPRVLRFTWSMKTTSPLMPDQIMQKIREVLDQNNCDYEQRERFVLWCVH 887
             |:.|:.        :|||.|||||||||||.:.|:::|.:||:|||.|||.:|.:|:::|.|||
 Frog   677 LTVLDKEKDKEDHRDSKPRSLRFTWSMKTTSSMEPNEMMSEIRKVLDANNCQHESQEKYMLLCVH 741

  Fly   888 GDPNTDSLVQWEIEVCKLPRLSLNGVRFKRISGTSIGFKNIASRIAFDLKL 938
            |.|..|:.||||:|||||||||||||||||||||||.||||||:||.:|||
 Frog   742 GTPGHDNYVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL 792

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	220/251 (88%)
		S_TKc	253..504	CDD:214567	220/250 (88%)
		UBA_MARK_Par1	525..563	CDD:270522	21/37 (57%)
		MARK1-3_C	839..936	CDD:213381	68/96 (71%)
mark2	XP_012808991.1	STKc_MARK	63..315	CDD:270974	220/251 (88%)
		UBA_MARK2	333..374	CDD:270589	22/40 (55%)
		MARK2_C	693..791	CDD:213386	68/97 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	458	1.000	Domainoid score	I486
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	742	1.000	Inparanoid score	I588
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000311
OrthoInspector	1	1.000	-	-		otm49044
Panther	1	1.100	-	-	O	PTHR24346
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X401
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.060