Protein Alignment par-1 and prkaa2

DIOPT Version :10

• Sequence 1: NP_995894.2
• Gene: par-1 / 2768852
• FlyBaseID: FBgn0260934
• Length: 1170
• Species: Drosophila melanogaster
• Sequence 2: XP_700831.4
• Gene: prkaa2 / 572074
• ZFINID: ZDB-GENE-081120-5
• Length: 553
• Species: Danio rerio
• Alignment Length: 322
• Identity: 138/322 - (42%)
• Similarity: 203/322 - (63%)
• Gaps: 17/322 - (5%)

  Fly   250 IGKYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGSLQ---KLFREVRIMKMLDHPN 311
            ||.|.|..|:|.|.|.|||:.:|..||.:||:||:::.::.  ||.   |:.||::.:|:..||:
Zfish    13 IGHYILGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIR--SLDVVGKIKREIQNLKLFRHPH 75

  Fly   312 IVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHRDL 376
            |:||:|||.|....:::|||.||||:|||:..|||:::.|||..|:||:|||.|||:..::||||
Zfish    76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEDAEARRLFQQIISAVDYCHRHMVVHRDL 140

  Fly   377 KAENLLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILY 441
            |.||:|||..:|.||||||.||..:.|..|.|.||||.|||||:..|:.|.|||||:||.|||||
Zfish   141 KPENVLLDGNMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILY 205

  Fly   442 TLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWMNM 506
            .|:.|:||||...:..|.:::..|.:.||.|::....:||...|.::|.|||:::.|...:|
Zfish   206 ALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVASLLMLMLQVDPLKRATIKDIREHEW--- 267

  Fly   507 GFEEDELKPYIEPK-----ADLADPKRI-EALVAMGYNRSEIEASL-SQVRYDDVFATYLLL 561
             |::| |..|:.|:     |.:.|.:.: |.........:|:.:|| |....|.:...|.|:
Zfish   268 -FKQD-LPGYLFPEDPSYDATVVDEEAVREVCEKFECTEAEVLSSLYSGDPQDQLAVAYHLI 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	120/254 (47%)
		UBA_MARK_Par1	525..563	CDD:270522	9/39 (23%)
		MARK1-3_C	839..936	CDD:213381
prkaa2	XP_700831.4	STKc_AMPK_alpha	13..268	CDD:270981	123/260 (47%)
		UBA_AID_AAPK2	285..349	CDD:270587	10/43 (23%)
		AMPKA_C_like	394..551	CDD:473060