Protein Alignment par-1 and Nuak1

DIOPT Version :9

• Sequence 1: NP_995894.2
• Gene: par-1 / 2768852
• FlyBaseID: FBgn0260934
• Length: 1170
• Species: Drosophila melanogaster
• Sequence 2: NP_001369005.1
• Gene: Nuak1 / 41256
• FlyBaseID: FBgn0262617
• Length: 2803
• Species: Drosophila melanogaster
• Alignment Length: 997
• Identity: 268/997 - (26%)
• Similarity: 417/997 - (41%)
• Gaps: 256/997 - (25%)

  Fly   198 GSGVAPTVNKNVLSTHSAHPSAIKQR-----TSSAKGSPNMQMRS-SAPMRWRATEEHIGKYKLI 256
            |:..|.....:......||||.|.|.     .|....:.|::|.: ...:|.|        :.:|
  Fly    17 GAEAAAPTGLDATGNSLAHPSGIPQDQIDNIMSGIANTGNVKMNNHRKKLRQR--------FDII 73

  Fly   257 KTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLN-PGSLQKLFREVRIMKMLDHPNIVKLFQVIE 320
            |.:|:|.:.||:|..:..||:|||||.|.|.::. ...|.::.|||:||..:.||||:.:::|.|
  Fly    74 KKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLVRIRREVQIMSSVHHPNIIHIYEVFE 138

  Fly   321 TEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDS 385
            ..:.:.|:||:|:|||::|||.....:.|:|||..|||:.:||.|||:.:|.|||||.||:|||.
  Fly   139 NREKMVLVMEFAAGGELYDYLSERKVLTEEEARRIFRQVATAVYYCHKHKICHRDLKLENILLDE 203

  Fly   386 ELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPF 450
            :.|.||||||.||.|.....|.||||||.||:||:.:|..|.|||||.|||||:|||||.||:||
  Fly   204 KGNAKIADFGLSNVFDDQRLLGTFCGSPLYASPEIVEGTPYQGPEVDCWSLGVLLYTLVYGSMPF 268

  Fly   451 DGSTLRELRERVLRGKY---RIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWMNMGFEEDE 512
            |||..:.|.:::.:|.|   |.|...||    |:|..|.:.|.||||:|.|....|:|   |.|.
  Fly   269 DGSNFKRLVKQISQGDYYEPRKPSRAST----LIRDMLTVCPRKRASIEQICSHWWVN---ENDN 326

  Fly   513 LKPYIEPKADLAD--PKRIEALVAMGYNRSEIEASLSQVRYDDVFATYLLLGRKSTDPESDGSRS 575
            :. .::...|||:  |.|::.|:::      ..|:::        |..|::      |.::
  Fly   327 VS-CLDLAEDLANQTPVRLDVLLSL------TPATIT--------ADQLVV------PSAE---- 366

  Fly   576 GSSLSLRNISGNDAGANAGSASVQSPTHRGVHRSISASSTKPSRRASSGVGPTNAAA------TV 634
                              |:|:.::..:..|.||.|..|.:       .:||.|..|      .|
  Fly   367 ------------------GAAAAKAAANERVPRSHSVGSIR-------DMGPPNTEAERRILDMV 406

  Fly   635 AAATGAVGAVNPSNNYNAAGSAADRASVGSNFKRQNTIDSATIKENTARLAAQNQRPASATQKML 699
            ||  |...|:.||                         .:.||  ..|:...|.:|....|....
  Fly   407 AA--GGEAALMPS-------------------------PTRTI--TPAQSPVQTKRKLQPTVSTE 442

  Fly   700 TTADTTLNSPAKPRTATKYDPTNGNRTVSGTSGIIPRRSTTLYEKTSSTEKTNVIPAET------ 758
            ..|.||.....||..::.....:|.........||..::|.:..:|.:.     ||.|.
  Fly   443 NAAGTTAKKKEKPANSSFVISKDGAPLTEAPPTIIEPQATLMEAETIAN-----IPEEVPVPSYS 502

  Fly   759 --------NLFDRLRMASAVKSSRHFPRNVPSRSTFHSGQ-TRARNNTALEYSGTSGASGDSSHP 814
                    ::.| |.|.:|..     |...|...|..:.| ||.:.:..:|......|
  Fly   503 QKDMQAVGDICD-LLMGTATT-----PAPAPPAPTPVARQPTRGKLDAVVETPEEKDA------- 554

  Fly   815 GRMSFFSKLSSRFSKRPTIAD----------EAAKPRVLRFTWSMKTTSPLMPDQIMQK--IREV 867
                  :|:..:|..:...||          :||.|           .|.:.|...::|  :::.
  Fly   555 ------TKVIKKFVNKHKTADLVNAINESASKAAAP-----------VSAVAPPPFVRKCSLQDE 602

  Fly   868 LDQNNCDYEQRERFVLWCVHGDPNTDSLVQWEIEVCKLP-----RLSLNGVRFKRISGTSIG-FK 926
            ...|..:.|:|:..:|       .|....|....|...|     :||:.||        |:| ||
  Fly   603 STLNKFNAERRKSRIL-------ETAEKFQPPPPVAAAPPEKPKKLSIPGV--------SVGSFK 652

  Fly   927 NIASRIAFDLKLXLNQTNNEGNA---AATASRPTDPTDTMTTTNCRRPSNDSTSRLSELSLLCRS 988
            ....:.|.:.......|..|..|   .|.|:......:|::|.   .||          .::.:|
  Fly   653 KEFEKKATNPPAAEGPTPGELRAQEQVAAAAAAAQEAETLSTP---PPS----------PVVAQS 704

  Fly   989 LTSQQGSQRRKKSRLSTGGSEDQKKS--NSLLSAFQMYSPFSSKENMQSSEEVEDLHVIDTQPGH 1051
            |   :||.  .|:.:::...::.::|  ||:....|..:. ||||..|...:.|.:.|.:
  Fly   705 L---EGSD--SKNSVASISLDEARRSMENSIALLLQAQNE-SSKEVDQLCAQTETIGVSE----- 758

  Fly  1052 SVDVPLFADFSPINPIMEEDAEGVEGGKTSEAKVISGGSGQKV-----KGDGGGGGGGNRLKRNI 1111
                          |..:::.|    .|...|:.|.|.:.|.|     ...|.|.|.||.:...:
  Fly   759 --------------PATQQERE----RKLKNARAIIGNAIQPVIRRPTPFYGIGNGFGNGMGGAV 805

  Fly  1112 KHTGSLIVRKLTAGRHNDADKK 1133
            ..:|:.:         |:|.|:
  Fly   806 GASGATV---------NNAPKR 818

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	123/255 (48%)
		S_TKc	253..504	CDD:214567	123/254 (48%)
		UBA_MARK_Par1	525..563	CDD:270522	6/39 (15%)
		MARK1-3_C	839..936	CDD:213381	21/104 (20%)
Nuak1	NP_001369005.1	STKc_NUAK	68..321	CDD:270975	124/264 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910