DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment par-1 and Gm5157

DIOPT Version :9

Sequence 1:	NP_995894.2	Gene:	par-1 / 2768852	FlyBaseID:	FBgn0260934	Length:	1170	Species:	Drosophila melanogaster
Sequence 2:	XP_011249060.1	Gene:	Gm5157 / 381937	MGIID:	3648211	Length:	301	Species:	Mus musculus

Alignment Length:	249	Identity:	116/249 - (46%)
Similarity:	170/249 - (68%)	Gaps:	7/249 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 YKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQ--LNPGSLQKLFREVRIMKMLDHPNIVKL 315
            ||::.|:|:|.|:.||.|.|:||...||:||:..|:  .:|     :.||.||||.|.||||:||
Mouse    27 YKMLNTLGEGKFSVVKRAFHVPTSTSVAVKILQNTKEYTSP-----ICREARIMKSLSHPNIIKL 86

  Fly   316 FQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAEN 380
            |.|::..:|.||:|||||.||:.|.::..|.::|.:.|..|.|||.||||||...|:|||:||.|
Mouse    87 FHVVQRRETTYLVMEYASEGELQDRIIKVGSLEESKTRRLFAQIVHAVQYCHDHHIVHRDIKASN 151

  Fly   381 LLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVS 445
            :|:|...|.|:.|||.:.|..||.||..|||:.||.||||.|.:||:||.||:|||||:|:.:||
Mouse   152 ILIDCRGNAKLCDFGLAAEVIPGQKLAGFCGTLPYCAPELLQAEKYEGPPVDIWSLGVLLFLMVS 216

  Fly   446 GSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIM 499
            |:|||.|.:..:|::.::...:.||.::..|..|::.:.|::||::|.::..||
Mouse   217 GNLPFQGKSFVDLKQEIISANFSIPSHVPIDIFNVIIELLMINPSRRPTIHQIM 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	116/249 (47%)
		S_TKc	253..504	CDD:214567	116/249 (47%)
		UBA_MARK_Par1	525..563	CDD:270522
		MARK1-3_C	839..936	CDD:213381
Gm5157	XP_011249060.1	STKc_AMPK-like	26..273	CDD:270905	116/249 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0586
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810