Protein Alignment par-1 and C27D6.11

DIOPT Version :10

• Sequence 1: NP_995894.2
• Gene: par-1 / 2768852
• FlyBaseID: FBgn0260934
• Length: 1170
• Species: Drosophila melanogaster
• Sequence 2: NP_001364716.1
• Gene: C27D6.11 / 3564833
• WormBaseID: WBGene00044388
• Length: 331
• Species: Caenorhabditis elegans
• Alignment Length: 316
• Identity: 102/316 - (32%)
• Similarity: 166/316 - (52%)
• Gaps: 23/316 - (7%)

  Fly   210 LSTHSAHPSAIKQRTSSAKGSPNMQMRSSAPMRWRATEEHIGKYKLIKTIGKGNFAKVKLAKHLP 274
            :|.:...|..:..:|.:.  :|.::            :||  |.|..|.:|.|::::|..|....
 Worm     9 VSENQEEPEELSPKTKAF--APTLE------------KEH--KLKFDKILGSGSYSRVARATWGD 57

  Fly   275 TGKEVAIKIID--KTQLNPGSLQK-LFREVRIMKMLDHPNIVKLFQVIETEKTLYLIMEYASGGE 336
            ...|||.|:|:  .|:.....::| |.||..|:|:|.|.||.:|:::|.....:..:.|:.:||:
 Worm    58 KKLEVAAKVINITSTREKDDYIKKFLPREKEIVKLLKHDNICRLYEMISFPDHIIFVTEFCAGGD 122

  Fly   337 VFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEFT 401
            :...:.....|.|.:|:..|||.::|:.:.....|:|||||.||:.||...|:|:.|||||....
 Worm   123 LLRKMKDIKTMNEDDAKFTFRQFIAALMHLQSYNIVHRDLKCENIFLDKHENVKLGDFGFSRILK 187

  Fly   402 PGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGK 466
            ||.|..|||||..|.|||:.:|::|.|..|||||.|||||.::.||:|||.....::.||.|..|
 Worm   188 PGEKSGTFCGSRAYVAPEILRGREYSGNAVDVWSTGVILYIMLVGSMPFDDRNPTKMIERQLAHK 252

  Fly   467 YRIPFYMSTDCEN--LLRKFLVLNPAKRASLETIMGDKWMNMGFEEDELKPYIEPK 520
            .:.|...:...::  |:.:.|..:...|.:.:.|...:|:..  :...:||...||
 Worm   253 IKFPKLCTASVQSKALILEILQPHAPNRPTYKAICESEWLKS--QPYYMKPDEHPK 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	91/256 (36%)
		UBA_MARK_Par1	525..563	CDD:270522
		MARK1-3_C	839..936	CDD:213381
C27D6.11	NP_001364716.1	Protein Kinases, catalytic domain	38..292	CDD:473864	89/253 (35%)