DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment par-1 and CG9222

DIOPT Version :9

Sequence 1:	NP_995894.2	Gene:	par-1 / 2768852	FlyBaseID:	FBgn0260934	Length:	1170	Species:	Drosophila melanogaster
Sequence 2:	NP_608999.2	Gene:	CG9222 / 33867	FlyBaseID:	FBgn0031784	Length:	337	Species:	Drosophila melanogaster

Alignment Length:	301	Identity:	110/301 - (36%)
Similarity:	162/301 - (53%)	Gaps:	34/301 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   217 PSAIKQRTSSAKGSPNMQMRSSAPMRWRATEEH---IGKYKLIKTIGKGNFAKVKLAKHLPTGKE 278
            ||.:....:..|..|...:          .|||   :|     |.||.||:||||:......||.
  Fly    52 PSGVVPVKADDKSKPQKTI----------LEEHGIILG-----KVIGTGNYAKVKIGFSEEYGKR 101

  Fly   279 VAIKIIDKTQLNPGSLQK-LFREVRIMKMLDHPNIVKLFQVIETEKTLYLIMEYASGGEVFDYLV 342
            ||:|||.|.:......|| |.||:..:|.|.|.|::..:|.|||...:||||:.|..|.:.||:.
  Fly   102 VAVKIISKVKAPSEYTQKFLPREIEAVKGLHHENLITFYQSIETSHRVYLIMQLAENGTLLDYVR 166

  Fly   343 LHGRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEFTPGSK-- 405
            ....:.|.::|..|:|:||||:|.|.|.::|||:|.||||||...|:|:.||||:.:.|..|.
  Fly   167 ERKFLDEPQSRTLFKQLVSAVEYIHSKGVVHRDIKCENLLLDENWNLKLIDFGFARKDTRTSDNQ 231

  Fly   406 ---LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKY 467
               ..|||||..||:||:.:|..||....|:|:.||:.|.:|.|.||:|||.:..|.:|:   ..
  Fly   232 VILSKTFCGSYAYASPEILKGVAYDPFMSDIWACGVVCYAMVFGRLPYDGSNVHILLKRI---NQ 293

  Fly   468 RIPF----YMSTDCENLLRKFLVLNPAK-RASLETIMGDKW 503
            .:.|    ..|::|::::..  :|.|.| |.::..:..|.|
  Fly   294 SLVFPKSPSASSECKHMIMH--ILAPVKIRYNIPQVKEDPW 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	102/263 (39%)
		S_TKc	253..504	CDD:214567	102/262 (39%)
		UBA_MARK_Par1	525..563	CDD:270522
		MARK1-3_C	839..936	CDD:213381
CG9222	NP_608999.2	STKc_TSSK4-like	75..333	CDD:271064	103/268 (38%)
CG9222	NP_608999.2	S_TKc	78..332	CDD:214567	102/263 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910