Protein Alignment par-1 and mark3a

DIOPT Version :9

• Sequence 1: NP_995894.2
• Gene: par-1 / 2768852
• FlyBaseID: FBgn0260934
• Length: 1170
• Species: Drosophila melanogaster
• Sequence 2: XP_021336197.1
• Gene: mark3a / 334300
• ZFINID: ZDB-GENE-030131-6232
• Length: 746
• Species: Danio rerio
• Alignment Length: 798
• Identity: 420/798 - (52%)
• Similarity: 505/798 - (63%)
• Gaps: 122/798 - (15%)

  Fly   203 PTVNKNVLSTHSAHPSAIKQRTSSAKGSPNMQMRSSAPMRWRATEEH--IGKYKLIKTIGKGNFA 265
            ||||:.....|:.:.....:.||.:..|......|.:.:    .:.|  ||.|:|:|||||||||
Zfish     9 PTVNERKAENHTTNGHGRSEVTSRSVRSSGRNRNSGSGL----DDVHPVIGNYRLLKTIGKGNFA 69

  Fly   266 KVKLAKHLPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNIVKLFQVIETEKTLYLIME 330
            |||||:|:.||.|||||:||||||||.|||||.|||.|||.|:||||||||:||||||||:|:||
Zfish    70 KVKLARHILTGSEVAIKMIDKTQLNPTSLQKLSREVTIMKNLNHPNIVKLFEVIETEKTLFLVME 134

  Fly   331 YASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFG 395
            ||||||||||||.||||||||||.|||||||||||||||||:||||||||||||.::||||||||
Zfish   135 YASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRIVHRDLKAENLLLDGDMNIKIADFG 199

  Fly   396 FSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRE 460
            |||||..||||||||||||||||||||||||||||||||||||||||||||||||||..|:||||
Zfish   200 FSNEFMVGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRE 264

  Fly   461 RVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWMNMGFEEDELKPYIEPKADLAD 525
            |||||||||||||||||||||::|||||||||.:||.||.::|:|.|||:|||||:.||.||::|
Zfish   265 RVLRGKYRIPFYMSTDCENLLKRFLVLNPAKRGTLEQIMKERWINSGFEDDELKPFTEPDADISD 329

  Fly   526 PKRIEALVAMGYNRSEIEASLSQVRYDDVFATYLLLGRKSTDPESDGSRSGSSLSLRNISGNDAG 590
            .|||:.:|.||:::.:|..||.::.||:|.|.|||||||:.:..||.| |.|:||:...
Zfish   330 QKRIDVIVGMGFSKEKIHESLFKMNYDEVTAIYLLLGRKTHEEVSDSS-SNSNLSVAKT------ 387

  Fly   591 ANAGSASVQSPTHRGVHRSISASSTKPSRRASSGVGPTNAAATVAAATGAVGAVNPSNNYNAAGS 655
            ..:...:.|||:|..|.||||:|.::.|||.|..||        ..|..|:
Zfish   388 RPSSEMNSQSPSHLKVQRSISSSESRKSRRHSEQVG--------VVANNAL-------------- 430

  Fly   656 AADRASVGSNFKR--QNTIDSATIKENTARLAAQ--NQRPASATQKMLTTADTTLNSPAKPRTAT 716
                    ||.||  ..|.|| .:|:....:|.:  |..|.|   .:|..|    |:|.|....
Zfish   431 --------SNSKRVVPVTADS-EVKQEGGVIARKLPNHSPPS---PLLGNA----NNPNKTEIP- 478

  Fly   717 KYDPTNGN----RTVSGTSGIIPRRSTTLYEKTSSTEKTNVIP-----------------AETNL 760
              |...||    ..:|| ||.:.||:|.:..:.::|::.:|||                 |.|:.
Zfish   479 --DRKKGNSITSNNISG-SGSMSRRNTYVCTERNNTDRLSVIPNGKENSVSLSPSSRDPGASTHS 540

  Fly   761 FDRLRMASAVKSSRHFPRNVPSRSTFHSGQTRARNNTALEYSGTSGASGD-SSHPGRMSFFSKLS 824
            ..    .|.......|||...|||||| ||.|.|....  |:|...:... .|.....:..:||:
Zfish   541 IS----TSVTPDKTRFPRGSASRSTFH-GQVRDRRTAT--YNGPPASPAQPRSRANANNLLTKLT 598

  Fly   825 S---------RFSKRPTIADEAA-------------------------KPRVLRFTWSMKTTSPL 855
            |         |||||.:...|.:                         |||.|||||||.|||.:
Zfish   599 SKLTRRNMSFRFSKRVSTEFERSGRFEGSSRHVSGDQQKDEGKDGKDGKPRSLRFTWSMNTTSTM 663

  Fly   856 MPDQIMQKIREVLDQNNCDYEQRERFVLWCVHGDPNTDSLVQWEIEVCKLPRLSLNGVRFKRISG 920
            .|..|:.:||.|||.|:|.|:|||.|:|.|.|||.:||||||||:||||||||||||||||||||
Zfish   664 EPADIINEIRTVLDANSCSYQQRECFLLLCAHGDSHTDSLVQWEMEVCKLPRLSLNGVRFKRISG 728

  Fly   921 TSIGFKNIASRIAFDLKL 938
            .||.||||||:||.:|||
Zfish   729 NSIAFKNIASKIAGELKL 746

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	216/251 (86%)
		S_TKc	253..504	CDD:214567	216/250 (86%)
		UBA_MARK_Par1	525..563	CDD:270522	18/37 (49%)
		MARK1-3_C	839..936	CDD:213381	70/96 (73%)
mark3a	XP_021336197.1	STKc_MARK	56..308	CDD:270974	216/251 (86%)
		UBA_like_SF	326..368	CDD:328731	20/41 (49%)
		MARK1-3_C	647..744	CDD:213381	70/96 (73%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	459	1.000	Domainoid score	I467
eggNOG	1	0.900	-	-		E1_KOG0586
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	743	1.000	Inparanoid score	I569
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000311
OrthoInspector	1	1.000	-	-		otm25828
orthoMCL	1	0.900	-	-		OOG6_101232
Panther	1	1.100	-	-	O	PTHR24346
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X401
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.820