DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment par-1 and CG4629

DIOPT Version :9

Sequence 1:	NP_995894.2	Gene:	par-1 / 2768852	FlyBaseID:	FBgn0260934	Length:	1170	Species:	Drosophila melanogaster
Sequence 2:	NP_608564.3	Gene:	CG4629 / 33284	FlyBaseID:	FBgn0031299	Length:	570	Species:	Drosophila melanogaster

Alignment Length:	441	Identity:	135/441 - (30%)
Similarity:	236/441 - (53%)	Gaps:	65/441 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   250 IGKYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKII--DKTQLNPGSLQKLFREVRIMKMLDHPNI 312
            ||.|:....||:|||:|||||.|..|..:||||::  |:..|:..:|:.|..|:..::.:.||||
  Fly    63 IGLYRFCGDIGRGNFSKVKLAVHQLTRDKVAIKVVDLDRAGLDAKALRMLSSEIATLECVHHPNI 127

  Fly   313 VKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLK 377
            ::||:|:||...:||:.|:..|||:::::...|.::|..|....:|::.||::.|....:|||:|
  Fly   128 LRLFEVVETLGRVYLVTEWIRGGELYNHITQGGPLREIHAAPLLKQLLLAVKHMHSLGYVHRDIK 192

  Fly   378 AENLLLDSELNIKIADFGFSNEFTPGS--KLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVIL 440
            |||:||.||..:|:||||||.:...|:  |||||||||||||||||....|.|..||||:||::|
  Fly   193 AENVLLLSEDRLKLADFGFSTQLINGANQKLDTFCGSPPYAAPELFSDDHYIGAPVDVWALGILL 257

  Fly   441 YTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKW-- 503
            |.:|.|::||...|:..|:..:|:|.|.:|..:|..|..|:::.|:..||:|.:::.::..::
  Fly   258 YFMVVGNMPFRAPTIPGLKAAILKGDYLLPGQLSLPCIRLIQRILIHIPAQRPTIDDMLNSQFVT 322

  Fly   504 ---MNMGFEEDELKPYIEP-KADL----ADPKRIEALVAMGYNRSEI----EASLSQVRYDDVFA 556
               ::....:.|:..:.:| |..:    :...|:....::....:|:    ..|::..:.|::|.
  Fly   323 CPKLSADLMQWEINQHTKPVKRSIFWVRSKSHRLRKSASLRDRYAEVVKKPAISMNTRQQDEMFV 387

  Fly   557 TYLL----LGRKSTDPESDGSRSGSSLSLRNISGNDAGANAGSASVQSPTHR-----GVHRSISA 612
            ...|    :|.:...|.|...:...|                :...:.||.|     .:.:.::.
  Fly   388 QNFLQPIEMGHELLVPVSSQLKEPQS----------------TEQAKRPTRRYMFCGSLKKKVTP 436

  Fly   613 SSTKPSRRASSGVGPTNAAATVAAATGAVGAVNPSN-----------NYNA 652
            ..|:|.::.::|      ..::.:|     .:||.|           ||:|
  Fly   437 METEPEKQLANG------GQSIGSA-----KINPWNVEVAEDCPLFKNYDA 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	107/260 (41%)
		S_TKc	253..504	CDD:214567	107/259 (41%)
		UBA_MARK_Par1	525..563	CDD:270522	6/45 (13%)
		MARK1-3_C	839..936	CDD:213381
CG4629	NP_608564.3	STKc_NIM1	63..321	CDD:270977	109/257 (42%)
CG4629	NP_608564.3	S_TKc	66..321	CDD:214567	107/254 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910