Protein Alignment par-1 and Pim2

DIOPT Version :10

• Sequence 1: NP_995894.2
• Gene: par-1 / 2768852
• FlyBaseID: FBgn0260934
• Length: 1170
• Species: Drosophila melanogaster
• Sequence 2: NP_001165574.1
• Gene: Pim2 / 317366
• -ID: -
• Length: 311
• Species: Rattus norvegicus
• Alignment Length: 305
• Identity: 91/305 - (29%)
• Similarity: 149/305 - (48%)
• Gaps: 23/305 - (7%)

  Fly   224 TSSAKGSPNMQMRSSAPMRWRATEEHIGKYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQ 288
            |...:|.|:..:..:.|...:.......:|:|...:|||.|..|.....:...::||||:|.:.:
  Rat     3 TKPLQGLPSPPVTPTQPPGGKDRAAFEAEYRLGPLLGKGGFGTVFAGHRVTDRRQVAIKVISRNR 67

  Fly   289 L-----------NPGSLQKLFREVRIMKMLDHPNIVKLFQVIETEKTLYLIMEY-ASGGEVFDYL 341
            :           .|..:..|:   ::.:...||.:::|....||.:...|::|. ....::|||:
  Rat    68 VLGWSTVSDSVTCPLEVALLW---KVGEGNGHPGVIRLLDWFETPEGFMLVLERPMPAQDLFDYI 129

  Fly   342 VLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLD-SELNIKIADFGFSNEFTPGSK 405
            ...|.:.|..:|..|.|:|:|||:||.:.::|||:|.||:|:| ...::|:.||| |........
  Rat   130 TEKGPLGESCSRSFFTQVVAAVQHCHARGVVHRDIKDENILIDLCRGSVKLIDFG-SGALLHDEP 193

  Fly   406 LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIP 470
            ...|.|:..|:.||.....:|......||||||:||.:|.|.:||      |..:.:|..:...|
  Rat   194 YTDFDGTRVYSPPEWISRHQYHALPATVWSLGVLLYDMVCGDIPF------ERDQEILEAELHFP 252

  Fly   471 FYMSTDCENLLRKFLVLNPAKRASLETIMGDKWMNMGFEEDELKP 515
            .::|.||..|:|:.|...|..|.|||.|:.|.||....||..:.|
  Rat   253 AHVSPDCCALIRRCLAPKPCSRPSLEEILLDPWMQTPAEEKPINP 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	82/264 (31%)
		UBA_MARK_Par1	525..563	CDD:270522
		MARK1-3_C	839..936	CDD:213381
Pim2	NP_001165574.1	Protein Kinases, catalytic domain	31..287	CDD:473864	83/265 (31%)