Protein Alignment par-1 and nimk-1

DIOPT Version :10

• Sequence 1: NP_995894.2
• Gene: par-1 / 2768852
• FlyBaseID: FBgn0260934
• Length: 1170
• Species: Drosophila melanogaster
• Sequence 2: NP_496679.3
• Gene: nimk-1 / 186015
• WormBaseID: WBGene00009867
• Length: 503
• Species: Caenorhabditis elegans
• Alignment Length: 531
• Identity: 164/531 - (30%)
• Similarity: 267/531 - (50%)
• Gaps: 89/531 - (16%)

  Fly   103 MMPIVTSSNSATSNSTAATPTPASGAAATGGVGSVSQGPATVSA----------SAANTNHSHQH 157
            |.|   |::|.:|:|..:....:.|.|..    :|...|.|.|:          |.|.:..|::.
 Worm     1 MQP---STSSPSSSSMGSRMRDSGGLARR----TVRSDPPTYSSILEYNVEEEVSEAESEESYEK 58

  Fly   158 SHQH--HHHVANNMTTDGARLSSNNSAVVASSAINHHHH---HTPGSGVAPTVNKNV--LSTHSA 215
            ..:|  ...|....:.||...:             ||||   :...|.|:..|.|.:  :|..:.
 Worm    59 PPEHVPARFVPTQRSDDGGYPA-------------HHHHEAFNRTVSAVSLPVGKQLKDMSEKTQ 110

  Fly   216 HPSAIKQRTSSAKGSPNMQMRSSAPMRWR--ATEEHIGKYKLIKTIGKGNFAKVKLAKHLPTGKE 278
            :..||.|..:.             |:..:  |....||.|:|.|.:|.|||:||||..|..|.::
 Worm   111 YERAILQLNND-------------PVVHKEVALGRRIGFYRLGKELGAGNFSKVKLGVHQLTKEK 162

  Fly   279 VAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVL 343
            ||:||:||.:::..:.:.|.||::.|:.::||||||||:|:||...::|::|||||||::.|:..
 Worm   163 VAVKIMDKAKMDAKAQKLLSREIQAMEEMNHPNIVKLFEVVETLTRVHLVIEYASGGELYTYVHE 227

  Fly   344 HGRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEFTPGSKLDT 408
            .|::.|.:|:..|.||||||.:.|.:.|:|||:||||::..|...:|:.|||||........|.|
 Worm   228 RGKLTEGDAKPLFAQIVSAVSHMHSRNIVHRDIKAENVMFSSPNTVKLVDFGFSCLVDREQMLRT 292

  Fly   409 FCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYM 473
            ||||||||||||||...|.|..||||:|||:|:.::.|..||...|:.:::..:..|||:||.|:
 Worm   293 FCGSPPYAAPELFQDTSYAGELVDVWALGVLLFFMLIGVTPFKAETVPDMKVLITAGKYQIPDYV 357

  Fly   474 STDCENLLRKFLVLNPAKRASLETIMGDKWM-NMGFEEDELKPYIEPKADLADPKR--------- 528
            |.....|::..|..:..:||.::::....|| :..|.:..|......|.|..:.|:
 Worm   358 SLLATELIKSMLKTDTGQRADIDSVKKHFWMRDCRFTKSYLSIKATAKIDNEEEKKAIDDKVWKI 422

  Fly   529 ------IEALVAMGYNRSEIEASLSQVRYDDVFATYLL-----------LGRKSTDPESDGS--R 574
                  ::.::        :|.:|.:...|.|..||.:           |.::..:|:...|  .
 Worm   423 LNNYGIVKEMI--------VEENLDKGPRDAVVGTYRIVQFQVQSEITRLAKEKDEPQPSSSSFT 479

  Fly   575 SGSSLSLRNIS 585
            :||..|:::::
 Worm   480 NGSPTSVKDVN 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	110/251 (44%)
		UBA_MARK_Par1	525..563	CDD:270522	8/63 (13%)
		MARK1-3_C	839..936	CDD:213381
nimk-1	NP_496679.3	STKc_NIM1	134..388	CDD:270977	112/253 (44%)