DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment par-1 and txt-2

DIOPT Version :9

Sequence 1:	NP_995894.2	Gene:	par-1 / 2768852	FlyBaseID:	FBgn0260934	Length:	1170	Species:	Drosophila melanogaster
Sequence 2:	NP_872128.2	Gene:	txt-2 / 178551	WormBaseID:	WBGene00019817	Length:	328	Species:	Caenorhabditis elegans

Alignment Length:	313	Identity:	101/313 - (32%)
Similarity:	160/313 - (51%)	Gaps:	38/313 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 SAHPSAIKQRTSSAKGSPNMQMRSSAPMRWRATEEHIGKYKLIKTIGKGNFAKVKLAKHLPT-GK 277
            :::.|..||..|:.|.|.:                   .|:.|:.:|:|:||:|.|...:.| .|
Worm     2 TSNMSTCKQFLSTKKKSKD-------------------SYEFIENLGEGSFAEVVLVAKVGTPNK 47

  Fly   278 EVAIKIIDKTQLNPGSLQKLFREVRIMKMLD---HPNIVKLFQVIETEKTLYLIMEYASGGEVFD 339
            ..|:|.|.....:...::.:.||..|.|.|.   |.|::.||::....:...||:.||.||::|:
Worm    48 MFAMKEISIVGKDECFMESIKRECSIQKRLSKSRHLNMIHLFEIRTNPENYQLILSYADGGDLFE 112

  Fly   340 YLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFS--NEFTP 402
            .:..||.:...||...|:|::..:::.|::.:.|||:|.|||||.....:|||||||:  :.|..
Worm   113 KINQHGGLGSDEAHRYFKQLIDGLRFIHEEGVTHRDIKPENLLLTKSGILKIADFGFATMHRFNG 177

  Fly   403 GSK-LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFD--------GSTLREL 458
            ..: |:.:||||||.|||:..|..|.||.||:||.||:|..:::|::|::        .|.....
Worm   178 AEQMLNAYCGSPPYIAPEVLTGIDYRGPAVDIWSAGVVLIAMIAGAVPWEQADHFDIFQSRYCSF 242

  Fly   459 RERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWMNMGFEED 511
            |....:|.:.   .||....:||||.| |....||::..|..|.|...|.|.|
Worm   243 RRNGRKGAWS---RMSQQVISLLRKIL-LQAELRATISMIEEDPWFIYGEEVD 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	91/266 (34%)
		S_TKc	253..504	CDD:214567	91/265 (34%)
		UBA_MARK_Par1	525..563	CDD:270522
		MARK1-3_C	839..936	CDD:213381
txt-2	NP_872128.2	PKc_like	22..284	CDD:389743	91/265 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D698464at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920