DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment par-1 and mekk-3

DIOPT Version :9

Sequence 1:	NP_995894.2	Gene:	par-1 / 2768852	FlyBaseID:	FBgn0260934	Length:	1170	Species:	Drosophila melanogaster
Sequence 2:	NP_492629.1	Gene:	mekk-3 / 172850	WormBaseID:	WBGene00013694	Length:	430	Species:	Caenorhabditis elegans

Alignment Length:	272	Identity:	86/272 - (31%)
Similarity:	136/272 - (50%)	Gaps:	44/272 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   252 KYKLIKTIGKGNFAKVKLAKHLPTGKE---VAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNIV 313
            :|.|.|.||:|....|.||:    ||:   .|:|||.|    .|.......:|..::||.|..||
Worm   156 RYSLGKLIGRGTLGSVYLAE----GKKGGTYAVKIISK----HGRHLPQEADVEYLRMLRHVRIV 212

  Fly   314 KLFQVIETEKT--LYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHRDL 376
            :...:||..|:  ::::|||...|.:.:|:...|.:..:..:...:||:..:::.|.|.|||:||
Worm   213 EYLYIIEPSKSNDIHILMEYMHTGSLQEYIARTGPLHHELVKAYAKQILEGLEFLHSKNIIHQDL 277

  Fly   377 KAENLLLDS---ELNIKIADFGFSNEFT------PGSKLDTFCGSPPYAAPELFQGKKYDGPEVD 432
            |..||||.:   |..||||||| |:.|:      .|.:..|    |.|..|.:..|:...|...|
Worm   278 KPANLLLKNTHRERLIKIADFG-SSRFSSLKREREGQQGRT----PKYTDPGVSLGRHVSGRRSD 337

  Fly   433 VWSLGVILYTLVSGSLPF--DG----STLRELRERVLRGKYRIPFYMSTD--CENLLR--KFLVL 487
            :||||||:..:.:|..|:  ||    :..|.|.|..       |.:.:::  .|||::  |.::.
Worm   338 IWSLGVIIIEMYTGVYPWSIDGEHPITVPRILDENP-------PNFTTSEKIDENLIKMAKLMLQ 395

  Fly   488 NPAKRASLETIM 499
            :.|||....|::
Worm   396 SVAKRPYASTLL 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	86/272 (32%)
		S_TKc	253..504	CDD:214567	86/271 (32%)
		UBA_MARK_Par1	525..563	CDD:270522
		MARK1-3_C	839..936	CDD:213381
mekk-3	NP_492629.1	S_TKc	157..412	CDD:214567	86/271 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000