DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment par-1 and LOC102551633

DIOPT Version :9

Sequence 1:	NP_995894.2	Gene:	par-1 / 2768852	FlyBaseID:	FBgn0260934	Length:	1170	Species:	Drosophila melanogaster
Sequence 2:	XP_038936415.1	Gene:	LOC102551633 / 102551633	RGDID:	7576862	Length:	474	Species:	Rattus norvegicus

Alignment Length:	473	Identity:	152/473 - (32%)
Similarity:	237/473 - (50%)	Gaps:	49/473 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   241 MRWRATEEHIGK-YKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGSLQKLFREVRIM 304
            |..::.|:.:|. ||::..:|:|:|..|.||.||.|...||||::   :::..::..:..|..|:
  Rat     1 MASKSKEKTLGSHYKILSYLGQGSFGTVNLAWHLKTQALVAIKML---EISKETISSILSERAIL 62

  Fly   305 KMLDHPNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQK 369
            :.|.||||::||||:.|...:..::|||.||.:|:.:...|.::|:.|:..|.|.||||:|||..
  Rat    63 ETLHHPNIIRLFQVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNL 127

  Fly   370 RIIHRDLKAENLLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVW 434
            .|:|||:|.:|:|.|:|.|.|:.|||.:.:|.||:.|...||:..:.||||...:.|:|.:.|||
  Rat   128 DIVHRDIKPQNILTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVW 192

  Fly   435 SLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIM 499
            ||||:||.:.:|..||.|.|.:::.:::..|.|.||.|.|...|||:.:.|.::|..|.|:|.|.
  Rat   193 SLGVLLYFISTGYCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIE 257

  Fly   500 GDKWMNMGFEEDELKPYIE-PKADLADPKRIEALVAMGYNRSEIEASLSQVRYDDVFATYLLLGR 563
            ...|:.        |..:. |.....|.|.:|.|..||||.::|..||.:.:||:..|.||:|..
  Rat   258 KHPWVR--------KCEVNIPTITCPDYKIVEMLCGMGYNANKILESLQKKKYDEPMAAYLILKD 314

  Fly   564 KSTDPESDGSRSGSSLSLRNISGNDAGANAGSASVQSPTHRGVHRSISASSTKPSRRASSGVGPT 628
            |.......|:.:           :|...:.|....|||.|.      |.|.....||||.   |.
  Rat   315 KVRQEIEHGTTT-----------SDMPVDQGPLPPQSPAHH------SVSGLPLKRRASE---PN 359

  Fly   629 NAAATVAAATGAVGAVNPSNNYNAAGSAADRASVGSNFKRQNTIDSATIKENTARLAAQNQRPAS 693
                     .|.:....|       |....|.:|..:..........|.|:|:...:|.:.||.:
  Rat   360 ---------FGLLHIWPP-------GEQVARHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVA 408

  Fly   694 ATQKMLTTADTTLNSPAK 711
            :.....|..:..:..|.|
  Rat   409 SPCVCNTILEIEIPLPTK 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	100/252 (40%)
		S_TKc	253..504	CDD:214567	100/250 (40%)
		UBA_MARK_Par1	525..563	CDD:270522	17/37 (46%)
		MARK1-3_C	839..936	CDD:213381
LOC102551633	XP_038936415.1	STKc_AMPK-like	13..261	CDD:270905	100/250 (40%)
LOC102551633	XP_038936415.1	UBA_MARK_Par1	275..314	CDD:270522	17/38 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910