Protein Alignment par-1 and mark4

DIOPT Version :9

• Sequence 1: NP_995894.2
• Gene: par-1 / 2768852
• FlyBaseID: FBgn0260934
• Length: 1170
• Species: Drosophila melanogaster
• Sequence 2: XP_012824414.1
• Gene: mark4 / 100491038
• XenbaseID: XB-GENE-6042140
• Length: 681
• Species: Xenopus tropicalis
• Alignment Length: 686
• Identity: 344/686 - (50%)
• Similarity: 424/686 - (61%)
• Gaps: 117/686 - (17%)

  Fly   218 SAIKQRTSSAKGSPNMQMRSSAPMRW---------RAT---EEHIGKYKLIKTIGKGNFAKVKLA 270
            :|..:|.:...||...: ::|.|:.|         |::   |.|:|.|:|::|||||||||||||
 Frog     5 TAGNERINDTSGSTRSE-KASTPLSWPPRPPGARSRSSVPEEPHVGNYRLLRTIGKGNFAKVKLA 68

  Fly   271 KHLPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNIVKLFQVIETEKTLYLIMEYASGG 335
            :|:.||:||||||||||||||.|||||||||||||.|:||||||||:||||||||||||||||||
 Frog    69 RHVLTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLIMEYASGG 133

  Fly   336 EVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEF 400
            |||||||.||||||||||.|||||||||.|||||.|:||||||||||||||.|||||||||||||
 Frog   134 EVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDSESNIKIADFGFSNEF 198

  Fly   401 TPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRG 465
            |||.||||||||||||||||||||:|:|||||||||||||||||||||||||..|:|||||||||
 Frog   199 TPGGKLDTFCGSPPYAAPELFQGKRYNGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRG 263

  Fly   466 KYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWMNMGFEEDELKPYIEPKADLADPKRIE 530
            |||||||||||||.:||:||||||:||.:|:.||.|||||:||:.|:||||.||:.|.|||||||
 Frog   264 KYRIPFYMSTDCEGVLRRFLVLNPSKRCTLDQIMNDKWMNIGFDSDDLKPYKEPEEDNADPKRIE 328

  Fly   531 ALVAMGYNRSEIEASLSQVRYDDVFATYLLLGRKSTDPESDG--SRSGSSLSL--RNISGNDAGA 591
            .::.|||:|.||:.:||..:|::|.|||||||||   |||:|  |||.|:|||  ..::.:....
 Frog   329 IMLEMGYSREEIKDALSSNKYNEVMATYLLLGRK---PESEGGESRSDSTLSLSRSRVASDVTNG 390

  Fly   592 NAGSASVQSPTHRGVHRSISASSTKPSRRASSGVGPTNAAATVAAATGAVGAVNPSNNYNAAGSA 656
            ...|:||.|...||..|         .||.|...||..|               ||....:....
 Frog   391 ATKSSSVHSKNQRGYQR---------QRRHSDFCGPAPA---------------PSQAKRSPPGV 431

  Fly   657 ADRASVGSNFKRQNTIDSATIKENTARLAAQ--------NQRPASATQKMLTTADTTLNSPAK-- 711
            .|..:||.                  |||.:        ..||...:..|::.|    ::|.|
 Frog   432 GDDGAVGE------------------RLAPRRGSGSVGGGSRPPPPSSPMVSHA----HNPNKAE 474

  Fly   712 -PRTATKYDPTNGNRTVSGTSGIIPRRSTTLYEKTSSTEKTNVI---------PAETNLFDRLRM 766
             |....:..||    |::...|::.||:|.:.....|:|:.:::         |:..........
 Frog   475 IPEPRKEAPPT----TINTPPGVMGRRNTYVCTDRHSSERHSLLHNDKENSSTPSRPPALSPSTQ 535

  Fly   767 ASAVKSSRHFPRNVPSRSTFHSGQTRARNNTALEYSGTSGASGDSSHP----------GRMSFFS 821
            :.|.:||.....||  |||||.|..|.|.       |.:......:||          ...:.||
 Frog   536 SIAERSSLSRGSNV--RSTFHGGHVRDRR-------GQNPPPSSPTHPHEGLNQSRTRATSNLFS 591

  Fly   822 KLSSRFSKRPTIADEAAKPRVLRFTWSMKTTSPLMP 857
            ||:|:.::|  :.||:.:      .|..:.|...:|
 Frog   592 KLTSKLTRR--VTDESER------VWRPEVTGSYIP 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	218/251 (87%)
		S_TKc	253..504	CDD:214567	218/250 (87%)
		UBA_MARK_Par1	525..563	CDD:270522	22/37 (59%)
		MARK1-3_C	839..936	CDD:213381	3/19 (16%)
mark4	XP_012824414.1	STKc_MARK	50..302	CDD:270974	218/251 (87%)
		UBA_MARK_Par1	323..361	CDD:270522	22/37 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	458	1.000	Domainoid score	I486
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000311
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X401
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.910