Protein Alignment par-1 and brsk2

DIOPT Version :10

• Sequence 1: NP_995894.2
• Gene: par-1 / 2768852
• FlyBaseID: FBgn0260934
• Length: 1170
• Species: Drosophila melanogaster
• Sequence 2: XP_004913517.1
• Gene: brsk2 / 100489211
• XenbaseID: XB-GENE-6469081
• Length: 840
• Species: Xenopus tropicalis
• Alignment Length: 911
• Identity: 247/911 - (27%)
• Similarity: 393/911 - (43%)
• Gaps: 214/911 - (23%)

  Fly   229 GSPNMQMRSSAPMRWRATEEHIGKYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGS 293
            |.|:||              ::|.|:|.||:|||....|||..|..|.::|||||:::.:|:...
 Frog    10 GIPHMQ--------------YVGPYRLEKTLGKGQTGLVKLGIHCVTCQKVAIKIVNREKLSESV 60

  Fly   294 LQKLFREVRIMKMLDHPNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQ 358
            |.|:.||:.|:|:::||:::||..|.|.:|.|||::|:.||||:|||||..||:..||||..|||
 Frog    61 LMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 125

  Fly   359 IVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQG 423
            |:||:.:||...|.|||||.||||||.:.||:|||||.::.....|.|:|.||||.||.||:.:|
 Frog   126 IISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRG 190

  Fly   424 KKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLN 488
            :||||.:.|:||.||||:.|:.|:||||...||:|.|:|.||.:.:|.::..||:|||...:.::
 Frog   191 EKYDGRKADIWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQNLLCGMIEVD 255

  Fly   489 PAKRASLETIMGDKWMNMGFEEDELKPYIE--------PKADLADPKRIEALVAMGYNRSE---I 542
            |.||.:||.|....|...|..|.|.:..:.        |..:..||..:|::.::|..|..   :
 Frog   256 PTKRLTLEAIQKHTWYIGGKNEPEPEQAVPRKVQVGSLPSLEDVDPDVLESMHSLGCFRDRNKLL 320

  Fly   543 EASLSQVRYDDVFATYLLLGRKSTDPESD-------------------------GSRSGSSLSLR 582
            :..||:....:....:|||.||...|..:                         |.|.....|:.
 Frog   321 QDLLSEEENQEKMIYFLLLDRKERYPSQEDEDLPPRVDIDPPRKRVDSPMLTRHGKRRPERKSME 385

  Fly   583 NISGNDAGANA-GSASVQSPTHRGVHRSISASSTKPSRRASSGVGPTNAAATVAAATGAVGAVNP 646
            .:||.|.|:.. ...:::...|....||||.        ||||:           :|..:.:..|
 Frog   386 VLSGTDGGSPVPARRAIEMAQHGQRSRSISG--------ASSGL-----------STSPISSPRP 431

  Fly   647 SNNYNAAGSAADRASVGSNFKRQNTIDSATIKENTARLAAQNQRPASATQKMLTT-----ADTTL 706
            ...:..                                .:|:..|.::..::||:     :|.||
 Frog   432 MRRFFP--------------------------------LSQSPTPPTSPHQILTSNPSGHSDPTL 464

  Fly   707 ------NSPAKPRTATKYDPTNGNRTVSGT--SGIIPRRSTTLYEKTSSTEKTNVIPAETNLFD- 762
                  ..|.|||.:.|...|..:..:..|  |.|.|:...  :.....|.:|   ||:..:.|
 Frog   465 AHPKTHTFPPKPRASEKPLQTTRSHPLPSTNFSCISPKSPN--HPAGQITCRT---PAKLAVSDL 524

  Fly   763 -----RLRMASAVKSSRHFPRNVPSRSTFHSGQTRARNNTALEYSGTSGASGDSSHP-GRMSFFS 821
                 .|...:...|.|..|...|..:..|:.:...        :||...:..||.. |.|.:.:
 Frog   525 APKSVPLIQVTPHPSPRGSPLPTPKGTPVHTPKESP--------AGTPSPTPPSSPSIGGMPWRT 581

  Fly   822 KLSS---------RFSKR----PTIADE------AAKPRVLRFTWSMKTTSPLMPDQIMQKIRE- 866
            :|:|         ||.:|    || |||      .:.|.:.:.:|.....:....|||...|::
 Frog   582 RLNSIKNNFLGSPRFHRRKLQVPT-ADEMTNLTPESSPELAKKSWFGNFLTLEKEDQIFVVIKDK 645

  Fly   867 ----------------------VLDQNNCDYEQRERFVLWCVHGDPNT-DSLVQWEIEVC----- 903
                                  |:.|.:...|.:..       |.|:. ...|::::::.
 Frog   646 PLSSIKADIVQAFLSIPSLSHSVISQTSFRAEYKST-------GGPSVFQKPVKFQVDITYTESG 703

  Fly   904 -KLPRLSLNGVRFKRISGTSIGFKNIASRIAFDLKLXLNQTNNEGNAAATASRPTDPTDTM---- 963
             |.....:..|.|..:||.|..||.:...|...|.. .:|        .:..:.:||.:.|
 Frog   704 EKQKDCGIYSVTFTLLSGPSRRFKRVVETIQTQLLSSHDQ--------PSVLQLSDPNNCMEYLS 760

  Fly   964 -TTTNCRRPSNDSTSRLSEL---------SLLCRSLTSQQGSQRRKKSRLSTGGSEDQKKSNSLL 1018
             ..:.|.||.::....|.:|         |......:.|:.:..:::..|...|.|..:|::..:
 Frog   761 GKLSKCGRPISNFFDVLKQLFSDEKNGHASPPPGPHSKQRPADNKEQGPLGASGKERARKTSPAI 825

  Fly  1019 S 1019
            :
 Frog   826 T 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	125/251 (50%)
		UBA_MARK_Par1	525..563	CDD:270522	10/40 (25%)
		MARK1-3_C	839..936	CDD:213381	21/126 (17%)
brsk2	XP_004913517.1	STKc_BRSK1_2	18..271	CDD:270983	126/252 (50%)
		UBA_BRSK	298..351	CDD:270525	13/52 (25%)