Protein Alignment mute and gon-4

DIOPT Version :9

• Sequence 1: NP_001097352.1
• Gene: mute / 2768848
• FlyBaseID: FBgn0085444
• Length: 1739
• Species: Drosophila melanogaster
• Sequence 2: NP_501864.2
• Gene: gon-4 / 177899
• WormBaseID: WBGene00001653
• Length: 1338
• Species: Caenorhabditis elegans
• Alignment Length: 1634
• Identity: 271/1634 - (16%)
• Similarity: 532/1634 - (32%)
• Gaps: 585/1634 - (35%)

  Fly     1 MPSSAKKSDSA---KSNSSTPRRPRKRKRVDRQSLDSQVDEDAKEIDRRLRKVAKKNSISAEDMQ 62
            |..:|::::.:   :.::||...|.:.:..:::..|.::....:..|..|...||..::|:.:::
 Worm     1 MEDTAEENNESIDDQPSTSTATDPNQTRETEKEKGDDEMFRLLQATDEILENKAKSMNLSSLNVR 65

  Fly    63 KVVRKVVRNDHVL-ALVTLKAEDEL-------AREKLESA-------EQQKRGAIIITDTPSVPK 112
            .::..:::....: .|:.::..|:|       :|:|.:.:       ..:|.||:.|.|..  ||
 Worm    66 SILHHLIKYPSTIDVLLGIRENDDLPSVRNMRSRKKPDDSGASSTVNTPKKFGALRIEDRG--PK 128

  Fly   113 LTRAKARELNCTPGISLPQLNETSTDNNGIEALIREDLHSDEEDEEYTFKEEDFHSDDDPNTTAS 177
            .......|.:........:.|:||| .|.:.|...||..:|:|:|   .::|....||:......
 Worm   129 SFLDLEYEEDDEYDDDYIEENDTST-RNKLNAGSEEDEENDDEEE---IEDEGEDEDDEEQDELE 189

  Fly   178 DFDSNPCTPQTPLTANEESPI------KFSDDGCFKVPLDRNFQDKEDLRIATRTRSKFCLQQTT 236
            :...:..|.....|:.:...:      :.|:|          .|::||.           :...|
 Worm   190 EDGEHEITGSEACTSGQNDTMHALLFDETSED----------VQNEEDY-----------VLNMT 233

  Fly   237 IEDLQSEFVPPDVEPSDVVENEMTANDADWMQFLNDFTKPLNNTVQGDD--------DDPINDPE 293
            :.|.::|.|.| :...|.|:::         .|..||...:|.|.:.:|        |||.::..
 Worm   234 LNDTRAESVAP-IPTLDNVDDD---------GFYRDFVTGINRTEKDNDNLEVLDTEDDPDDEDY 288

  Fly   294 YVAAD---HLESEYENAEELRDVNISKKELTDLVSELFAGLLEEGVSL-----ESIELETPQKF- 349
            .|.||   ::| :::...:.:...|.:.||..|:.:..  |.|:.:.|     |:|..|..:|.
 Worm   289 NVCADDGLNVE-DWDETRQDKTTQIPRHELKALMIDTL--LAEKEIPLNAFPEEAINGEEHRKSQ 350

  Fly   350 -VESANVSMIPIDQVSRNIDFDGQQINANQQELSVFQPNLMPPPCEGNEMGMGVPVPVAVLQEET 413
             |:.|.|    .::::.:|....:..:..:..|:.|:|.      |..::.|.:...|.:|.:
 Worm   351 KVKDAEV----YERINTSISSSSESCSLLKDSLATFRPQ------ELQQLNMQLEQHVQLLTQ-- 403

  Fly   414 GGSACNVVNIPSEALTVPPELIAVPIPGQPNCFQIAKVVGNDSTVGLPLTEETLQNFSSLHPMEP 478
                                                                             
 Worm   404 ----------------------------------------------------------------- 403

  Fly   479 PVVAASNGDRYKKPFDTNFTWEYISVRKHIYSEYEEKFESLRNVEPVNLNHLARSRGFTQSQHDM 543
             :|...:.|                                     |||:|:..|.....::.|.
 Worm   404 -LVVTCHHD-------------------------------------VNLSHVRNSSQLMMNELDD 430

  Fly   544 LQQQLRIHTQLLSQSYLQTYSHPTLYPMAKKPREMLEELHKMATKDPSFNCWNLQEAVQLVRKWE 608
            ::||                   .:||..                   |:..||..|::..
 Worm   431 IRQQ-------------------KIYPTV-------------------FDVRNLDAAIESC---- 453

  Fly   609 HDLSSDEFKEENEKMMDFINKETDLTDGHTRQVPRLAPRIMDLMLDSRVFMYPQYLPRMAFQPKL 673
            ||:::.:..:|:     |: |..:.|:|:....  |.|....::..|....||..||  :.||..
 Worm   454 HDINAFDAVDES-----FL-KYAENTEGYGGIA--LRPEAAVVLSRSNAIRYPALLP--SRQPFF 508

  Fly   674 TQT-TAYAPSEYQLIAIGLEKHLALMVKAKRQLRKGADPIRVACKRMIKDTICGKTARRIFLKIA 737
            .:| ..:...|..::|:.|.:...|..:.::::......|:..|       :..:::.:|...:.
 Worm   509 IETPIPFLSEEDLMLAVALLQFAHLPRRGEKEMIDRYTAIQQHC-------LPARSSYKIRTHLK 566

  Fly   738 ELRNSKQYNPVKYFFEHRRAPPANAIL----WGFAGGLVRTPRERHMELP---------SGWQYY 789
            .:|.|.: ||:....:.........:|    |            :..:.|         .||...
 Worm   567 SMRRSDK-NPIHQIMQAAEKGVCKLVLPLKSW------------QESDTPICQWPPASQPGWYRR 618

  Fly   790 IEKTWDQKRTRRNFKASKASSVAS-----------ASYLEFVREAVGEDLLLPETFGQAAVPNGS 843
            .::|::....|:..:...::.|.:           ||...|.....|||   .|.......|:|.
 Worm   619 FQETFNVTEERKILRKHVSTMVLTPVKNKDRQDQEASEATFESGEEGED---DEFVNMGTAPDGR 680

  Fly   844 --AAGSE----------PPKESKPKKRPAQRRPRP---------AENPPQLTINVNYVFGGNT-- 885
              ..|.|          ...|..|.||  ::.|.|         .|...::..:.....||.|
 Worm   681 KIIMGREHIEDLVHQLIKQNEISPSKR--RKNPTPMKLSTMIQLEEAEKRIADSQKNSCGGQTIS 743

  Fly   886 SAGNIPGVSGVS---------VPLVAGGNLAENVLNINRSLYTAAECSSLLALPPAPPPLDENAP 941
            :..|:.|.|.|.         :|..:..:..|::.|...|.:            |.|.|:.:.
 Worm   744 ALSNVSGDSNVDNNGTHEKELMPSTSSIDSLESINNQETSKF------------PRPLPMSDQ-- 794

  Fly   942 PAINFTVDKFTNTLQI--------------CELEESSKAVQPDLLPAQDTPSVPGRNA------- 985
            |.:|.:....|.|..:              .|:..|......:...:...|..|||.:
 Worm   795 PTLNTSCHITTTTCSVSYEDVDVGTLKKSYVEITASKYETNSNSCFSYPIPPTPGRRSPDDFDDY 859

  Fly   986 -----------KRARYQIF-----KPKVQSANKSRK--------------------GSTPTR--- 1011
                       .:..|.:.     .|:..||::|.:                    .||..:
 Worm   860 FMDLESNSLMWPQTPYAVTDENPQTPRGFSASESSEPIDFSSLGKATSLDTEEIVFQSTSCQRPM 924

  Fly  1012 ---------SRYHILRERLRHKLSQRCHSLITTYESYLRH------------HIEKYKDCELVQV 1055
                     |....|.|.:.....||     |..||.:..            :.|..::| :::.
 Worm   925 GYCSDFGEFSNSSSLPEEIPVPSHQR-----TPQESAIEDDSSMPGLDMVPLYEEDVEEC-IIED 983

  Fly  1056 VHNRFFALELYTQLLVDLR--------MFCSNTNSKTAAQPKRSRSDDEAA-------KLRRANR 1105
            :......::   |.||:.|        :....||  .|...||:|.:.||.       :.....:
 Worm   984 IEEEEAPIK---QGLVNSRPPLRFKKEVKAGITN--LAPSRKRTRIEREAMGSVGLDDEQLHDKQ 1043

  Fly  1106 QEEMLRQMLQPDTTEERNRKDAIFAMNFYEKVEEALLSANRLDDCKKFNSILQNFDPRQEKVSSL 1170
            :|.::|:::     |:.|:: .....:.|::.:||:...|           |.:|    |||:..
 Worm  1044 KENIMRKVI-----EDVNQR-LFMHTDTYQRFKEAITDEN-----------LTDF----EKVTRT 1087

  Fly  1171 YLKVEEILLPTHPELAEVFLNFLL---PAEAAEMGKFFEH---------FMICNATNFINKLNIY 1223
            .     |:|..||||    ||.:|   |.||.......:|         .||.:...:|....:
 Worm  1088 I-----IILANHPEL----LNLVLLNAPPEAVISDLQCDHNYQSYKVAIEMIMDIERYITAAKL- 1142

  Fly  1224 FSKQPAQIRKIYACLNE-LAEMPNVS------------------MKKVEN-------KIMPLLKG 1262
              |:|: ::.::..:.. |.:.||::                  .||:|:       |..|.|:.
 Worm  1143 --KEPS-LKGLFRYIQSFLEDKPNMTDEQATKRFYELFGQDRPLWKKLESRFWCLPYKARPRLEN 1204

  Fly  1263 NQFL-------------IDW------------------FVQQFPQGKPPKRILSPV-ETINLHDV 1295
            .:::             .||                  .|.:..:.:||..::... |....:|.
 Worm  1205 YEYIDLTGLETMSKREKRDWNSIPPRFETVDDIDQVMGSVYRASKNEPPSNLVVKCGEFCIRNDD 1269

  Fly  1296 QNNTTGEYTE--------------------TIQEFTDVPTPSKPGCHLKYINGRIFYGAKILLPA 1340
            :..|..|.||                    ||..||....||        :...:.:|.|.:: |
 Worm  1270 ETYTQLEITERLWTRKDDISLLTSYNEALKTIPNFTVSQMPS--------LISDLSFGEKSII-A 1325

  Fly  1341 KLSFMAASI 1349
            :|.::...:
 Worm  1326 RLQYLLTEL 1334

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159760
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR16088
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030