DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33459 and Proz

DIOPT Version :9

Sequence 1:	NP_995855.2	Gene:	CG33459 / 2768847	FlyBaseID:	FBgn0053459	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_080110.1	Gene:	Proz / 66901	MGIID:	1860488	Length:	399	Species:	Mus musculus

Alignment Length:	200	Identity:	46/200 - (23%)
Similarity:	75/200 - (37%)	Gaps:	35/200 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 STPWMAFLHN-HLQFLCGGSLITSEFVLTAAHCVMPTPKNLTVRLGEYDWTRQMDSINPKHRHRE 111
            |.||...|.| ..:..|.|.|:..:||||.|.|.: ...|::|:..    ..|...|...|.|..
Mouse   192 SFPWQVRLTNSEGEDFCAGVLLQEDFVLTTAKCSL-LHSNISVKAN----VDQRIRIKSTHVHMR 251

  Fly   112 YMVTRIYTHPSYRSIAAYDIALLKLNQTVEYTVAIRPICLVLPENFHEWYWLVDSVEDFTLTGWG 176
            |          .......|::||:|.:.::...:..|:|  :||.....:.|:...|.. |:||.
Mouse   252 Y----------DEESGENDVSLLQLEEPLQCPSSGLPVC--VPERDFAEHVLIPGTEGL-LSGWM 303

  Fly   177 ATKTEPVSQVL-------------QSANLTQIDRGTCHDR---YGHSVDHTHICAGSSKSFACVG 225
            ...|...:..:             |:.|:|...|.:|...   .|..|:.:.:......::...|
Mouse   304 LNGTHLATTPMLLSVTQADGEECGQTLNVTVTTRTSCEKGSVVMGPWVEGSVVTREHKGTWFLTG 368

  Fly   226 DSGSP 230
            ..|||
Mouse   369 ILGSP 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33459	NP_995855.2	Tryp_SPc	37..272	CDD:214473	45/199 (23%)
CG33459	NP_995855.2	Tryp_SPc	38..272	CDD:238113	45/199 (23%)
Proz	NP_080110.1	GLA	23..85	CDD:214503
		EGF_CA	<95..122	CDD:238011
		FXa_inhibition	136..165	CDD:291342
		Tryp_SPc	192..397	CDD:304450	45/199 (23%)
		Trypsin	192..>340	CDD:278516	39/165 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24278
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100