DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33459 and PRSS56

DIOPT Version :9

Sequence 1:	NP_995855.2	Gene:	CG33459 / 2768847	FlyBaseID:	FBgn0053459	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_001356777.1	Gene:	PRSS56 / 646960	HGNCID:	39433	Length:	604	Species:	Homo sapiens

Alignment Length:	249	Identity:	76/249 - (30%)
Similarity:	108/249 - (43%)	Gaps:	33/249 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 RIFGGMDAGLVSTPWMAFLHNHLQFLCGGSLITSEFVLTAAHCVMPTPKNL--TVRLGEYDWTRQ 99
            ||.||..|...:.||:..|....|.||||.|:.:.:|||||||.:..|..|  ||.|.|.....|
Human   104 RIVGGSAAPPGAWPWLVRLQLGGQPLCGGVLVAASWVLTAAHCFVGAPNELLWTVTLAEGSRGEQ 168

  Fly   100 MDSINPKHRHREYMVTRIYTHPSYRSIAAY-DIALLKLNQTVEYTVAIRPICLVLPENFHEWYWL 163
            .:         |..|.||..||.:.....: |:||::|...|....:.||:|  ||:...|
Human   169 AE---------EVPVNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVC--LPQEPQE---- 218

  Fly   164 VDSVEDFTLTGWGAT-KTEPVSQVLQSANLTQIDRGTCHDRYGHSV-DHTHICAG--SSKSFACV 224
            ..:.....:.||||. :..|.::.::.|.:..:...||....|..: ..|.:|||  :....:|.
Human   219 PPAGTACAIAGWGALFEDGPEAEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQ 283

  Fly   225 GDSGSPLAMKVVHNRRYIHAQVGIVSRGPKNCDGV------TVFTNVVSFTEWI 272
            ||||.||... ....|......|:.|.|    ||.      .|:|.|..|.:|:
Human   284 GDSGGPLTCS-EPGPRPREVLFGVTSWG----DGCGEPGKPGVYTRVAVFKDWL 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33459	NP_995855.2	Tryp_SPc	37..272	CDD:214473	75/247 (30%)
CG33459	NP_995855.2	Tryp_SPc	38..272	CDD:238113	74/246 (30%)
PRSS56	NP_001356777.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	64..96
		Tryp_SPc	105..335	CDD:238113	75/248 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	443..475
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	574..604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158882
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24278
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.940