Protein Alignment CG33459 and PRSS2

DIOPT Version :10

• Sequence 1: NP_995855.2
• Gene: CG33459 / 2768847
• FlyBaseID: FBgn0053459
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 68/258 - (26%)
• Similarity: 104/258 - (40%)
• Gaps: 49/258 - (18%)

  Fly    37 RIFGGMDAGLVSTPWMAFLHNHLQFLCGGSLITSEFVLTAAHCVMPTPKN-----------LTVR 90
            :|.||......|.|:...|::...| ||||||:.::|::|.||......:           :.||
Human    23 KIVGGYICEENSVPYQVSLNSGYHF-CGGSLISEQWVVSAGHCYKSAINSKLSGRGCEYHRIQVR 86

  Fly    91 LGEYDWTRQMDSINPKHRHREYM-VTRIYTHPSYRS-IAAYDIALLKLNQTVEYTVAIRPICL-V 152
            |||:       :|.....:.::: ..:|..||.|.| ....||.|:||:........:..|.| .
Human    87 LGEH-------NIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISLPT 144

  Fly   153 LPENFHEWYWLVDSVEDFTLTGWGATKTEPVS--QVLQSANLTQIDRGTCHDRYGHSVDHTHICA 215
            .|.         .:..:..::|||.|.:....  ..||..:...:.:..|...|...:.:...|.
Human   145 APP---------AAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCV 200

  Fly   216 G--SSKSFACVGDSGSPLAMKVVHNRRYIHAQVGIVSRG----PKNCDGVTVFTNVVSFTEWI 272
            |  .....:|.||||.|    ||.|...    .||||.|    .||..|  |:|.|.::.:||
Human   201 GFLEGGKDSCQGDSGGP----VVSNGEL----QGIVSWGYGCAQKNRPG--VYTKVYNYVDWI 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33459	NP_995855.2	Tryp_SPc	37..272	CDD:214473	66/256 (26%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	68/257 (26%)