DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33459 and proca

DIOPT Version :9

Sequence 1:	NP_995855.2	Gene:	CG33459 / 2768847	FlyBaseID:	FBgn0053459	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_956650.1	Gene:	proca / 393327	ZFINID:	ZDB-GENE-060824-5	Length:	434	Species:	Danio rerio

Alignment Length:	274	Identity:	85/274 - (31%)
Similarity:	123/274 - (44%)	Gaps:	46/274 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 EPNCGQI----------------PFRMRIFGGMDAGLVSTPWMAFLHNHL-QFLCGGSLITSEFV 73
            :.:||||                |:   :.||.......:||.|.:.||| :|.|||.||...:|
Zfish   170 DASCGQIRIPKSAYANKPKPVLQPW---VMGGNVGKRGESPWQALILNHLGRFHCGGVLIDENWV 231

  Fly    74 LTAAHCVMPTPKNLTVRLGEYDWTRQMDS--INPKHRHREYMVTRIYTHPSYRSIAA-YDIALLK 135
            |||||| :.|....:||||:|...:...|  ..|..:|        .:||.|..|.. .|||||:
Zfish   232 LTAAHC-LETSSKFSVRLGDYQRFKFEGSEVTLPVKQH--------ISHPQYNPITVDNDIALLR 287

  Fly   136 LNQTVEYTVAIRPICLVLPENFHEWYWLVDSVEDFTLTGWGATKTEPVS--QVLQSANLTQIDRG 198
            |:..|:::..|.|.||...|..........:|.  .:||||.......|  ..|....|..:|..
Zfish   288 LDGPVKFSTYILPACLPSLELAKRMLHRNGTVT--IITGWGKNNQSATSYNSTLHYVELPIVDNK 350

  Fly   199 TCHDRYGHSVDHTHICAG--SSKSFACVGDSGSPLAMKVVHNRRYIHAQVGIVSRGPKNC---DG 258
            .|.....:::....:|||  .....||.||||.|: |.:.|:..::   ||:||.| :.|   |.
Zfish   351 ECSRHMMNNLSDNMLCAGVLGQVKDACEGDSGGPM-MTLFHDTWFL---VGLVSWG-EGCGQRDK 410

  Fly   259 VTVFTNVVSFTEWI 272
            :.::|.|.|:.:||
Zfish   411 LGIYTKVASYLDWI 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33459	NP_995855.2	Tryp_SPc	37..272	CDD:214473	78/245 (32%)
CG33459	NP_995855.2	Tryp_SPc	38..272	CDD:238113	78/244 (32%)
proca	NP_956650.1	GLA	23..84	CDD:214503
		EGF_CA	85..119	CDD:238011
		FXa_inhibition	128..165	CDD:291342
		Tryp_SPc	195..427	CDD:238113	80/246 (33%)
		Tryp_SPc	197..424	CDD:214473	78/242 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24278
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010