Protein Alignment CG33459 and KLK1

DIOPT Version :10

• Sequence 1: NP_995855.2
• Gene: CG33459 / 2768847
• FlyBaseID: FBgn0053459
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 74/275 - (26%)
• Similarity: 115/275 - (41%)
• Gaps: 43/275 - (15%)

  Fly    17 LLYGLAVLLEPNCGQIPFRMRIFGGMDAGLVSTPWMAFLHNHLQFLCGGSLITSEFVLTAAHCVM 81
            |:..||:.|.......|.:.||.||.:....|.||.|.|::...|.|||.|:..::|||||||:
Human     4 LVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCI- 67

  Fly    82 PTPKNLTVRLGEYDW-----TRQMDSINPKHRHREYMVTRIYTH-----PSYRSIAAYDIALLKL 136
              ..|..:.||.::.     |.|...::....|..:.::.:..|     ..|    ::|:.||:|
Human    68 --SDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDY----SHDLMLLRL 126

  Fly   137 NQTVE-YTVAIRPICLVLPENFHEWYWLVDSVEDFTL-TGWGATKTEPVS--QVLQSANLTQIDR 197
            .:..: .|.|::.:.|...|         ..|....| :|||:.:.|..|  ..||..:|..:..
Human   127 TEPADTITDAVKVVELPTEE---------PEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPN 182

  Fly   198 GTCHDRYGHSVDHTHICAG--SSKSFACVGDSGSPLAMKVVHNRRYIHAQVGIVSRGPKNC---D 257
            ..|...:...|....:|.|  ......||||||.||....|..        |:.|.|...|   :
Human   183 DECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQ--------GVTSWGYVPCGTPN 239

  Fly   258 GVTVFTNVVSFTEWI 272
            ..:|...|:|:.:||
Human   240 KPSVAVRVLSYVKWI 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33459	NP_995855.2	Tryp_SPc	37..272	CDD:214473	67/253 (26%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	68/254 (27%)