DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33459 and f9a

DIOPT Version :9

Sequence 1:	NP_995855.2	Gene:	CG33459 / 2768847	FlyBaseID:	FBgn0053459	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_878288.2	Gene:	f9a / 359826	ZFINID:	ZDB-GENE-030714-2	Length:	503	Species:	Danio rerio

Alignment Length:	253	Identity:	83/253 - (32%)
Similarity:	123/253 - (48%)	Gaps:	26/253 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RMRIFGGMDAGLVSTPWMAFL--HNHLQFLCGGSLITSEFVLTAAHCVMPTPK-NLTVRLGEYDW 96
            :.||.||..|.....||...|  .:..|..||||::...:|:|||||::.... :..:|:||:|
Zfish   251 KSRIIGGNSALPGEIPWQVALVSRSTQQVFCGGSILNPLWVITAAHCLLGNHNGSFYIRVGEHD- 314

  Fly    97 TRQMDSINPKHRHREYMVTRIYTHPSYR---SIAAYDIALLKLNQTVEYTVAIRPICLVLPENFH 158
               :..|....::.:  |.::.:||.|.   |:..:|||||:|...:..|..:|||||. |..|.
Zfish   315 ---VSKIEGTEQNVD--VIKLISHPRYNSKVSLFNHDIALLRLRSPIRLTPTVRPICLG-PMVFS 373

  Fly   159 EWYWLVDSVEDFTLTGWGATKTEPVS-QVLQSANLTQIDRGTCHDRYGHSVDHTHICAGSSKS-- 220
            .  .|:.|....|::|||..:.:..| ..||...|..:||..|.:.....:.|...|||.|.|
Zfish   374 N--TLLQSGTLATVSGWGRVRFQGRSAATLQKIELPYVDRTVCKESSSDPITHFMFCAGHSDSPK 436

  Fly   221 FACVGDSGSPLAMKVVHNRRYIHAQVGIVSRGPKNC---DGVTVFTNVVSFTEWIFRT 275
            .||.||||.|..|: .||..::   .||:|.| :.|   ....|:|.|.::..||..|
Zfish   437 DACQGDSGGPHVMR-YHNTWFL---TGIISWG-EECAKKGKYGVYTQVGNYYRWIQHT 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33459	NP_995855.2	Tryp_SPc	37..272	CDD:214473	80/246 (33%)
CG33459	NP_995855.2	Tryp_SPc	38..272	CDD:238113	79/245 (32%)
f9a	NP_878288.2	GLA	19..83	CDD:214503
		EGF_CA	84..120	CDD:238011
		FXa_inhibition	127..163	CDD:291342
		Tryp_SPc	253..486	CDD:214473	80/246 (33%)
		Tryp_SPc	254..489	CDD:238113	81/248 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24278
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010