DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33459 and F10

DIOPT Version :9

Sequence 1:	NP_995855.2	Gene:	CG33459 / 2768847	FlyBaseID:	FBgn0053459	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_058839.1	Gene:	F10 / 29243	RGDID:	61850	Length:	482	Species:	Rattus norvegicus

Alignment Length:	259	Identity:	76/259 - (29%)
Similarity:	116/259 - (44%)	Gaps:	44/259 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 MRIFGGMDAGLVSTPWMAFLHN--HLQFLCGGSLITSEFVLTAAHCVMPTPKNLTVRLGEYDWTR 98
            :||.||.:......||.|.|.:  .....|||:::...::|||||| :...|...||:|:.: |.
  Rat   230 IRIVGGQECKRGECPWQALLFSDEETDGFCGGTILNEFYILTAAHC-LHQAKRFKVRVGDLN-TE 292

  Fly    99 QMDSINPKHRHREYMVTRIYTHPSY-RSIAAYDIALLKLNQTVEYTVAIRPICLVLPENFHEWYW 162
            |.|.....|.     |..|..|..: |....:|||:|:|...:.:...:.|.|  ||:.  :|
  Rat   293 QEDGGEMVHE-----VDMIIKHNKFQRDTYDFDIAMLRLKTPITFRENVAPAC--LPQK--DW-- 346

  Fly   163 LVDSVEDFTL--------TGWGATKTE-PVSQVLQSANLTQIDRGTCHDRYGHSVDHTHICAG-- 216
                 .:.||        :|:|.|..: ..|:||:...:..:||.||......|:.....|||
  Rat   347 -----AEATLMTQKTGIVSGFGRTHEKGRQSKVLKMMEVPYVDRNTCRLSTSFSITQNMFCAGYD 406

  Fly   217 SSKSFACVGDSGSPLAMKVVHNRRY--IHAQVGIVSRGPKNC---DGVTVFTNVVSFTEWIFRT 275
            :.:..||.||||.|      |..|:  .:...||||.| :.|   ....::|.|.:|.:||.|:
  Rat   407 AKQEDACQGDSGGP------HVTRFKDTYFVTGIVSWG-EGCARKGKYGIYTKVTAFLKWIDRS 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33459	NP_995855.2	Tryp_SPc	37..272	CDD:214473	73/253 (29%)
CG33459	NP_995855.2	Tryp_SPc	38..272	CDD:238113	72/252 (29%)
F10	NP_058839.1	GLA	23..84	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:405372
		Tryp_SPc	232..462	CDD:238113	74/254 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24278
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010