DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33459 and f10

DIOPT Version :9

Sequence 1:	NP_995855.2	Gene:	CG33459 / 2768847	FlyBaseID:	FBgn0053459	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_958870.3	Gene:	f10 / 282670	ZFINID:	ZDB-GENE-021206-9	Length:	504	Species:	Danio rerio

Alignment Length:	250	Identity:	76/250 - (30%)
Similarity:	125/250 - (50%)	Gaps:	35/250 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 RIFGGMDAGLVSTPWMAFL--HNHLQFLCGGSLITSEFVLTAAHCVMPTPKNLTVR--LGEYDWT 97
            ||..|::......||.|.|  .|::.| |||:::|..|:|:||||:   .::|::|  :|||
Zfish   244 RIVNGVECPPGDCPWQALLINENNMGF-CGGTILTEHFILSAAHCM---NESLSIRVVVGEY--- 301

  Fly    98 RQMDSINPKHRHREYMVTRIYTHPSYRSIAAY-DIALLKLNQTVEYTVAIRPICLVLPE-NFHEW 160
               |::.|:.|...:.|..|..|.:|:....: ||||:||::.:::|..|.|.|  ||| .|.|
Zfish   302 ---DTLVPEGREATHDVDEILIHKNYQPDTYHNDIALIKLSKPIKFTKYIIPAC--LPEMKFAE- 360

  Fly   161 YWLVDSVEDFTLTGWGATKTEPVSQ-VLQSANLTQIDRGTCHDRYGHSVDHTHICAG--SSKSFA 222
             .::...:|..::|:|..:...:|. :||...:..::|..|.:.....:.....|||  ..:..|
Zfish   361 -RVLMQQDDGLVSGFGRVREGGLSSTILQKLTVPYVNRAKCIESSNFKISGRMFCAGYDQEEKDA 424

  Fly   223 CVGDSGSPLAMKVVHNRRYIHAQ--VGIVSRGPKNC---DGVTVFTNVVSFTEWI 272
            |.||||.|      |..|:.:..  .|:||.| :.|   ....|:|.|..:..||
Zfish   425 CQGDSGGP------HVTRFKNTWFITGVVSWG-EGCARKGKYGVYTQVSKYIMWI 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33459	NP_995855.2	Tryp_SPc	37..272	CDD:214473	74/248 (30%)
CG33459	NP_995855.2	Tryp_SPc	38..272	CDD:238113	73/247 (30%)
f10	NP_958870.3	GLA	19..82	CDD:214503
		EGF_CA	83..119	CDD:238011
		FXa_inhibition	126..161	CDD:291342
		Tryp_SPc	244..472	CDD:214473	74/248 (30%)
		Tryp_SPc	245..474	CDD:238113	74/248 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24278
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010