DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33459 and F7

DIOPT Version :9

Sequence 1:	NP_995855.2	Gene:	CG33459 / 2768847	FlyBaseID:	FBgn0053459	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_690059.1	Gene:	F7 / 260320	RGDID:	628678	Length:	446	Species:	Rattus norvegicus

Alignment Length:	291	Identity:	87/291 - (29%)
Similarity:	127/291 - (43%)	Gaps:	62/291 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LEPNCGQIPF---------RMRIFGGMDAGLVSTPWMAFLHNHLQFLCGGSLITSEFVLTAAHCV 80
            :|..||:||.         :.||.||........||.|.|..:...|||..|:.:.:::|||||.
  Rat   172 VEYPCGRIPVVEKRNFSRPQGRIVGGYVCPKGECPWQAVLKFNEALLCGAVLLDTRWIVTAAHCF 236

  Fly    81 MPTPK--NLTVRLGEYDW-----TRQMDSINPKHRHREYMVTRIYTHPSYRSIAAYDIALLKLNQ 138
            ....|  |:||.|||:|:     |.|:..:      .:.::...||    |....:||||::|::
  Rat   237 DKFGKLVNITVVLGEHDFSEKEGTEQVRLV------EQVIMPNKYT----RGRTDHDIALVRLHR 291

  Fly   139 TVEYTVAIRPICLVLPENFHEWYWLVDSVEDFTLTGW------GATKTEPVSQVLQSANLTQIDR 197
            .|.:|..:.|:|  |||.......|. |:....::||      |||..|  ..|::...|...|
  Rat   292 PVTFTDYVVPLC--LPERAFSENTLA-SIRFSRVSGWGQLLDRGATALE--LMVIEVPRLMTQD- 350

  Fly   198 GTCHDRYGHSVDHTHI-----CAG--SSKSFACVGDSGSPLAMKVVHNRRYIHAQVGIVSRGPKN 255
              |.:...||.:...|     |||  .....||.||||.|.|.. .|...|:   .|:||.| :.
  Rat   351 --CLEHAKHSANTPRITENMFCAGYMDGTKDACKGDSGGPHATH-YHGTWYL---TGVVSWG-EG 408

  Fly   256 CDG---VTVFTNVVSFTEWIFRTTLYDAKYM 283
            |..   :.|:|.|..:.:|:       .|||
  Rat   409 CAAIGHIGVYTRVSQYIDWL-------VKYM 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33459	NP_995855.2	Tryp_SPc	37..272	CDD:214473	78/257 (30%)
CG33459	NP_995855.2	Tryp_SPc	38..272	CDD:238113	77/256 (30%)
F7	NP_690059.1	GLA	25..85	CDD:214503
		EGF_CA	87..123	CDD:238011
		Tryp_SPc	194..430	CDD:238113	78/265 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24278
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100