DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33459 and F9

DIOPT Version :9

Sequence 1:	NP_995855.2	Gene:	CG33459 / 2768847	FlyBaseID:	FBgn0053459	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_000124.1	Gene:	F9 / 2158	HGNCID:	3551	Length:	461	Species:	Homo sapiens

Alignment Length:	255	Identity:	74/255 - (29%)
Similarity:	115/255 - (45%)	Gaps:	37/255 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 RIFGGMDAGLVSTPWMAFLHNHLQFLCGGSLITSEFVLTAAHCVMPTPKNLTVRLGEYDWTRQMD 101
            |:.||.||.....||...|:..:...||||::..::::|||||| .|...:||..||::..
Human   226 RVVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCV-ETGVKITVVAGEHNIE---- 285

  Fly   102 SINPKHRHREYMVTRIYTHPSYR-SIAAY--DIALLKLNQTVEYTVAIRPICLVLPE------NF 157
              ..:|..::..|.||..|.:|. :|..|  |||||:|::.:.....:.|||:...|      .|
Human   286 --ETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKF 348

  Fly   158 HEWYWLVDSVEDFTLTGWGATKTEPVSQ-VLQSANLTQIDRGTCHDRYGHSVDHTHICAGSSKS- 220
            ...|          ::|||....:..|. |||...:..:||.||......::.:...|||..:.
Human   349 GSGY----------VSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGG 403

  Fly   221 -FACVGDSGSPLAMKVVHNRRYIHAQVGIVSRGPKNC---DGVTVFTNVVSFTEWIFRTT 276
             .:|.||||.|...: |....::   .||:|.| :.|   ....::|.|..:..||...|
Human   404 RDSCQGDSGGPHVTE-VEGTSFL---TGIISWG-EECAMKGKYGIYTKVSRYVNWIKEKT 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33459	NP_995855.2	Tryp_SPc	37..272	CDD:214473	71/249 (29%)
CG33459	NP_995855.2	Tryp_SPc	38..272	CDD:238113	70/248 (28%)
F9	NP_000124.1	GLA	28..92	CDD:214503
		EGF_CA	93..129	CDD:238011
		FXa_inhibition	134..170	CDD:317114
		Tryp_SPc	227..457	CDD:238113	72/251 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24278
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010