Protein Alignment CG33458 and KLK4

DIOPT Version :10

• Sequence 1: NP_995854.2
• Gene: CG33458 / 2768846
• FlyBaseID: FBgn0053458
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 74/292 - (25%)
• Similarity: 113/292 - (38%)
• Gaps: 76/292 - (26%)

  Fly     8 LALLILGHGISLGYSYLLEWDCGISKYTYRITGGRDSPLMLNPWLAYLHINSKFICGGSLLNHWF 72
            |..||||...||           :|....:|..|.|......||.|.|.:.::..|.|.|::..:
Human    12 LGYLILGVAGSL-----------VSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQW 65

  Fly    73 VLTAAHCFRDKNAKVLVRLG-------ENDASQKIDCNESECAAPHLEYMIMQKLIHPLYRTAHY 130
            ||:|||||::   ...:.||       :...||.:   |:..:..|.||.      .||...
Human    66 VLSAAHCFQN---SYTIGLGLHSLEADQEPGSQMV---EASLSVRHPEYN------RPLLAN--- 115

  Fly   131 YDIALAKLNRYVVYTDSIRPI------------CLMLNPNWQVYVDTIRYFIITGWGATNASEVS 183
             |:.|.||:..|..:|:||.|            ||                 ::|||......:.
Human   116 -DLMLIKLDESVSESDTIRSISIASQCPTAGNSCL-----------------VSGWGLLANGRMP 162

  Fly   184 DKLQLTRIPQIDRFTCRYWFGYMVDRTHICA--GESKHYVGKGDSGGPLGSMVDYKYAKRFFQFG 246
            ..||...:..:....|...:..:...:..||  |:.:.....|||||||       ....:.| |
Human   163 TVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQDQKDSCNGDSGGPL-------ICNGYLQ-G 219

  Fly   247 IVSHLRQPFHGV---SVFTNILSYSNWIHRTI 275
            :||..:.|...|   .|:||:..::.||.:|:
Human   220 LVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	65/259 (25%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	65/259 (25%)