Protein Alignment CG33458 and TMPRSS13

DIOPT Version :10

• Sequence 1: NP_995854.2
• Gene: CG33458 / 2768846
• FlyBaseID: FBgn0053458
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_001070731.1
• Gene: TMPRSS13 / 84000
• HGNCID: 29808
• Length: 567
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 83/287 - (28%)
• Similarity: 122/287 - (42%)
• Gaps: 72/287 - (25%)

  Fly    17 ISLGYSYLLEWDCGISKYTYRITGGRDSPLMLNPWLAYLHINSKFICGGSLLNHWFVLTAAHCFR 81
            |||..|:     ||:...|.||.||..:.....||...||..:..||||:|::..:||||||||.
Human   310 ISLQCSH-----CGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFF 369

  Fly    82 DKNAKVL----VRLGENDASQKIDCNESECAAPHLEYMIMQKLIHPLYRTAH-YYDIALAKLNRY 141
            ....|||    |..|.::..|.     .|.|:      |.:.:|:..|.... .|||||.:|::.
Human   370 VTREKVLEGWKVYAGTSNLHQL-----PEAAS------IAEIIINSNYTDEEDDYDIALMRLSKP 423

  Fly   142 VVYTDSIRPICLMLNPN--------WQVYVDTIRYFIITGWGATNASEVSDK----LQLTRIPQI 194
            :..:..|.|.||.::..        |           |||:|.|.  |..||    |:..::..|
Human   424 LTLSAHIHPACLPMHGQTFSLNETCW-----------ITGFGKTR--ETDDKTSPFLREVQVNLI 475

  Fly   195 DRFTCRYWF---GYMVDRTHICAGESKHYVG-----KGDSGGPLGSMVDYKYAKRFFQFGIVS-- 249
            |...|..:.   .|:..|. :|||:.:   |     :|||||||..    :...|::..|:.|
Human   476 DFKKCNDYLVYDSYLTPRM-MCAGDLR---GGRDSCQGDSGGPLVC----EQNNRWYLAGVTSWG 532

  Fly   250 ----HLRQPFHGVSVFTNILSYSNWIH 272
                ...:|    .|:|.:.....||:
Human   533 TGCGQRNKP----GVYTKVTEVLPWIY 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	75/266 (28%)
TMPRSS13	NP_001070731.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..115
		PHA03378	<9..148	CDD:223065
		13 X 5 AA repeats of A-S-P-A-[GLQR]	9..93
		4 X 5 AA repeats of T-P-P-G-R	14..68
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	131..157
		SRCR_2	231..321	CDD:464747	6/15 (40%)
		Tryp_SPc	325..554	CDD:214473	74/264 (28%)