DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33458 and f7

DIOPT Version :9

Sequence 1:	NP_995854.2	Gene:	CG33458 / 2768846	FlyBaseID:	FBgn0053458	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_001072819.1	Gene:	f7 / 780280	XenbaseID:	XB-GENE-5787186	Length:	452	Species:	Xenopus tropicalis

Alignment Length:	287	Identity:	89/287 - (31%)
Similarity:	126/287 - (43%)	Gaps:	54/287 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 GISLGYSYL-----LEWDCG-------ISKYTYRITGGRDSPLMLNPWLAYLHINSKFICGGSLL 68
            |..||...|     :.:.||       ::|.. ||.||...|....||.|.|..|..|||||:|:
Frog   179 GYKLGADGLSCEPTVNYPCGKIPVLKNVNKRA-RIVGGDMCPKGECPWQALLMYNEIFICGGTLI 242

  Fly    69 NHWFVLTAAHCFRD-KNAKVLVRLGENDASQKIDCNESECAAPHLEYMIMQKLIHPLYRTAHYY- 131
            ...:|:|||||.:. ...|:.|.|||:    :|...|.......:..:||.:         |||
Frog   243 APNWVITAAHCLKPLPENKLTVVLGEH----RIGTPEGTEQESKVSKIIMHE---------HYYG 294

  Fly   132 -------DIALAKLNRYVVYTDSIRPICLMLNPNWQVYVD---TIRYFIITGWG-ATNASEVSDK 185
                   ||||.||...|.|||.:.|:||   |..|..|.   :|||..::||| ...:....:.
Frog   295 SKTNNDNDIALLKLTTPVNYTDYVVPLCL---PEKQFAVQELLSIRYSTVSGWGRLLESGATPEL 356

  Fly   186 LQLTRIPQIDRFTCRYWFGYMVDRTHICAG--ESKHYVGKGDSGGPLGSMVDYKYAKRFFQFGIV 248
            ||..::|::....|.......:.:...|||  :......|||||||..:    :|....|..|||
Frog   357 LQRVQLPRVKTQDCIRQTQMNISQNMFCAGYTDGSKDSCKGDSGGPHAT----QYKNTHFLTGIV 417

  Fly   249 SH----LRQPFHGVSVFTNILSYSNWI 271
            |.    .::..:|  |:|.:..|:.||
Frog   418 SWGLGCAKKEKYG--VYTRVSRYTEWI 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33458	NP_995854.2	Tryp_SPc	37..271	CDD:214473	80/252 (32%)
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	81/253 (32%)
f7	NP_001072819.1	Gla	67..107	CDD:366184
		EGF_CA	108..144	CDD:238011
		FXa_inhibition	153..189	CDD:373209	4/9 (44%)
		Tryp_SPc	212..445	CDD:238113	81/253 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24278
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010