DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33458 and Proz

DIOPT Version :9

Sequence 1:	NP_995854.2	Gene:	CG33458 / 2768846	FlyBaseID:	FBgn0053458	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_080110.1	Gene:	Proz / 66901	MGIID:	1860488	Length:	399	Species:	Mus musculus

Alignment Length:	237	Identity:	53/237 - (22%)
Similarity:	84/237 - (35%)	Gaps:	53/237 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 PWLAYL-HINSKFICGGSLLNHWFVLTAAHCFRDKNAKVLVRLGENDASQKIDCNESECAAPHLE 113
            ||...| :...:..|.|.||...||||.|.|          .|..::.|.|.:.::        .
Mouse   194 PWQVRLTNSEGEDFCAGVLLQEDFVLTTAKC----------SLLHSNISVKANVDQ--------R 240

  Fly   114 YMIMQKLIHPLY-RTAHYYDIALAKLNRYVVYTDSIRPICL--------MLNPNWQVYVDTIRYF 169
            ..|....:|..| ..:...|::|.:|...:....|..|:|:        :|.|..:        .
Mouse   241 IRIKSTHVHMRYDEESGENDVSLLQLEEPLQCPSSGLPVCVPERDFAEHVLIPGTE--------G 297

  Fly   170 IITGWGATNASEVSDKLQLTRIPQIDRFTCRYWFGYMVDRTHICAGESKHYVGKGD-SGGPL--G 231
            :::|| ..|.:.::....|..:.|.|...|.......|.....|.        ||. ..||.  |
Mouse   298 LLSGW-MLNGTHLATTPMLLSVTQADGEECGQTLNVTVTTRTSCE--------KGSVVMGPWVEG 353

  Fly   232 SMVDYKYAKRFFQFGIVSHLRQPFHGVS---VFTNILSYSNW 270
            |:|..::...:|..||:.....|  |.|   :.|.:..||.|
Mouse   354 SVVTREHKGTWFLTGILGSPPPP--GQSQMLLLTAVPRYSMW 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33458	NP_995854.2	Tryp_SPc	37..271	CDD:214473	53/237 (22%)
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	53/237 (22%)
Proz	NP_080110.1	GLA	23..85	CDD:214503
		EGF_CA	<95..122	CDD:238011
		FXa_inhibition	136..165	CDD:291342
		Tryp_SPc	192..397	CDD:304450	53/237 (22%)
		Trypsin	192..>340	CDD:278516	35/172 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24278
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100