Protein Alignment CG33458 and TMPRSS4

DIOPT Version :10

• Sequence 1: NP_995854.2
• Gene: CG33458 / 2768846
• FlyBaseID: FBgn0053458
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: XP_005271670.1
• Gene: TMPRSS4 / 56649
• HGNCID: 11878
• Length: 494
• Species: Homo sapiens
• Alignment Length: 300
• Identity: 93/300 - (31%)
• Similarity: 134/300 - (44%)
• Gaps: 72/300 - (24%)

  Fly     5 PALLALLILGHGISLGYSYLLEWDCGISKYTYRITGGRDSPLMLNPWLAYLHINSKFICGGSLLN 69
            |.|...|:..|.::          ||.|..|.|:.|..::.:...||...:..:.:.:||||:|:
Human   182 PCLSGSLVSLHCLA----------CGKSLKTPRVVGVEEASVDSWPWQVSIQYDKQHVCGGSILD 236

  Fly    70 -HWFVLTAAHCFRDKNAKVL---VRLGENDASQKIDCNESECAAPHLEYMIMQKLIHPLYRTAHY 130
             || ||||||||| |:..|.   ||.|    |.|:....|...|   :.:|::  .:|:|...:
Human   237 PHW-VLTAAHCFR-KHTDVFNWKVRAG----SDKLGSFPSLAVA---KIIIIE--FNPMYPKDN- 289

  Fly   131 YDIALAKLNRYVVYTDSIRPICLML--------NPNWQVYVDTIRYFIITGWGAT--NASEVSDK 185
             ||||.||...:.::.::|||||..        .|.|           |.|||.|  |..::||.
Human   290 -DIALMKLQFPLTFSGTVRPICLPFFDEELTPATPLW-----------IIGWGFTKQNGGKMSDI 342

  Fly   186 LQLTRIPQIDRFTCRYWFGYMVDRTH--ICAGESKHYVG--KGDSGGPLGSMVDYKYAKRFFQFG 246
            |....:..||...|.....|..:.|.  :|||..:..|.  :|||||||....|     ::...|
Human   343 LLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSD-----QWHVVG 402

  Fly   247 IVSHLRQPFHGV------SVFTNILSYSNWIH-----RTI 275
            |||.    .:|.      .|:|.:.:|.|||:     |||
Human   403 IVSW----GYGCGGPSTPGVYTKVSAYLNWIYNVWKDRTI 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	81/264 (31%)
TMPRSS4	XP_005271670.1	LDLa	58..92	CDD:238060
		SRCR_2	108..197	CDD:470597	4/24 (17%)
		Tryp_SPc	204..429	CDD:214473	80/257 (31%)