Protein Alignment CG33458 and KLK6

DIOPT Version :10

• Sequence 1: NP_995854.2
• Gene: CG33458 / 2768846
• FlyBaseID: FBgn0053458
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Alignment Length: 234
• Identity: 70/234 - (29%)
• Similarity: 116/234 - (49%)
• Gaps: 32/234 - (13%)

  Fly    49 NPWLAYLHINSKFICGGSLLNHWFVLTAAHCFRDKNAKVLVRLGENDASQKIDCNESECAAPHLE 113
            :|:.|.|:.:...:|||.|::..:|||||||   |...:.|.||:::..|:....|        :
Human    33 HPYQAALYTSGHLLCGGVLIHPLWVLTAAHC---KKPNLQVFLGKHNLRQRESSQE--------Q 86

  Fly   114 YMIMQKLIHPLYRTA-HYYDIALAKLNRYVVYTDSIRPICLMLNPNWQVYVDTIRYFIITGWGAT 177
            ..:::.:|||.|..| |..||.|.:|.|....::.|:|:.|..:.:    .:|....|: |||.|
Human    87 SSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCS----ANTTSCHIL-GWGKT 146

  Fly   178 NASEVSDKLQLTRIPQIDRFTCRYWFGYMVDRTHICAGESKHYVGK----GDSGGPLGSMVDYKY 238
            ...:..|.:|...|..:.|..|.:.:...:.:..:|||:.|:  ||    |||||||   |...:
Human   147 ADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKY--GKDSCQGDSGGPL---VCGDH 206

  Fly   239 AKRFFQFGIV--SHLRQPFHGVSVFTNILSYSNWIHRTI 275
            .:....:|.:  ....:|    .|:||:..|:|||.:||
Human   207 LRGLVSWGNIPCGSKEKP----GVYTNVCRYTNWIQKTI 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	68/231 (29%)
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	66/228 (29%)