Protein Alignment CG33458 and PRSS2

DIOPT Version :10

• Sequence 1: NP_995854.2
• Gene: CG33458 / 2768846
• FlyBaseID: FBgn0053458
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 71/248 - (28%)
• Similarity: 112/248 - (45%)
• Gaps: 52/248 - (20%)

  Fly    57 INSKF-ICGGSLLNHWFVLTAAHCFRDK-NAK----------VLVRLGENDASQKIDCNESECAA 109
            :||.: .|||||::..:|::|.||::.. |:|          :.|||||::. :.::.||
Human    41 LNSGYHFCGGSLISEQWVVSAGHCYKSAINSKLSGRGCEYHRIQVRLGEHNI-EVLEGNE----- 99

  Fly   110 PHLEYMIMQKLI-HPLY--RTAHYYDIALAKLNRYVVYTDSIRPICLMLNPNWQVYVDTIRYFII 171
               :::...|:| ||.|  ||.. .||.|.||:...|....:..|.|   |.......|  ..:|
Human   100 ---QFINAAKIIRHPKYNSRTLD-NDILLIKLSSPAVINSRVSAISL---PTAPPAAGT--ESLI 155

  Fly   172 TGWGAT--NASEVSDKLQLTRIPQIDRFTCRYWFGYMVDRTHICAG--ESKHYVGKGDSGGPLGS 232
            :|||.|  :.::..|:||....|.:.:..|...:...:.....|.|  |......:||||||:.|
Human   156 SGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGGKDSCQGDSGGPVVS 220

  Fly   233 MVDYKYAKRFFQFGIVS------HLRQPFHGVSVFTNILSYSNWIHRTIITNS 279
            ..:.:        ||||      ...:|    .|:|.:.:|.:||..||..||
Human   221 NGELQ--------GIVSWGYGCAQKNRP----GVYTKVYNYVDWIKDTIAANS 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	67/241 (28%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	67/241 (28%)