Protein Alignment CG33458 and PRSS1

DIOPT Version :10

• Sequence 1: NP_995854.2
• Gene: CG33458 / 2768846
• FlyBaseID: FBgn0053458
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 72/258 - (27%)
• Similarity: 115/258 - (44%)
• Gaps: 48/258 - (18%)

  Fly    37 RITGGRDSPLMLNPWLAYLHINSKFICGGSLLNHWFVLTAAHCFRDKNAKVLVRLGENDASQKID 101
            :|.||.:......|:...|:....| |||||:|..:|::|.||::   :::.|||||::. :.::
Human    23 KIVGGYNCEENSVPYQVSLNSGYHF-CGGSLINEQWVVSAGHCYK---SRIQVRLGEHNI-EVLE 82

  Fly   102 CNESECAAPHLEYMIMQKLI-HPLY-RTAHYYDIALAKLNRYVVYTDSIRPICLMLNPNWQVYVD 164
            .||        :::...|:| ||.| |.....||.|.||:...|....:..|.|...|     ..
Human    83 GNE--------QFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAP-----PA 134

  Fly   165 TIRYFIITGWG--ATNASEVSDKLQLTRIPQIDRFTCRYWFGYMVDRTHICAG--ESKHYVGKGD 225
            |....:|:|||  |::.::..|:||....|.:.:..|...:...:.....|.|  |......:||
Human   135 TGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGD 199

  Fly   226 SGGPL---GSMVDYKYAKRFFQFGIVS------HLRQPFHGVSVFTNILSYSNWIHRTIITNS 279
            ||||:   |.:.           |:||      ...:|    .|:|.:.:|..||..||..||
Human   200 SGGPVVCNGQLQ-----------GVVSWGDGCAQKNKP----GVYTKVYNYVKWIKNTIAANS 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	68/250 (27%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	66/248 (27%)