DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33458 and prozb

DIOPT Version :9

Sequence 1:	NP_995854.2	Gene:	CG33458 / 2768846	FlyBaseID:	FBgn0053458	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_001313449.1	Gene:	prozb / 558106	ZFINID:	ZDB-GENE-120816-1	Length:	395	Species:	Danio rerio

Alignment Length:	277	Identity:	55/277 - (19%)
Similarity:	95/277 - (34%)	Gaps:	76/277 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 YTYRITGGRDSPLMLNP----------------W-LAYLHINSKFICGGSLLNHWFVLTAAHCFR 81
            ||....|...||.:.||                | :.:|:.:...:|.|.:|....:||:|.|..
Zfish   158 YTLNSDGRSCSPNVQNPCGTTEMSSFCPDGRCSWEVRFLNASGHDVCHGVILGQKSILTSATCMT 222

  Fly    82 D-KNAKVLVRLGENDASQKIDCNESECAAPHLEYMIMQKLIHPLYRTAHYYDIALAKLNRYVVYT 145
            . ::....|.:|.:.|:.::     ....||..::           :....|:...:|.......
Zfish   223 ALQDLHFTVAVGVSTAAVRV-----SSWTPHKRFL-----------SGPDDDLCFLELQEPFPPN 271

  Fly   146 DSIRPICLMLNPNWQVYVDTI-----RYFIITGWGAT----NASEVSDKLQLTRIPQIDRFTCRY 201
            .|..|:||   |. :.|.:.|     |..:..| |||    :..:..|.|.||
Zfish   272 ISTVPLCL---PE-KDYSENILMRAGREGVAEG-GATYSYLSLDDCRDALNLT------------ 319

  Fly   202 WFGYMVDRTHIC-----AGESKHYVGKGDSGGPLGSMVDYKYAKRFFQFGIVSHLRQPFHGVSVF 261
               :::.....|     ||..:..|   .||.|..::    ..|..|..| ||..........:|
Zfish   320 ---FVMTNKMFCMKRESAGSERCTV---SSGSPAATL----EGKTAFLTG-VSLSAGRCGDTLLF 373

  Fly   262 TNILSYSNWIHRTIITN 278
            |.:..|.:|:...::.:
Zfish   374 TKLSRYLHWLRPLLLAS 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33458	NP_995854.2	Tryp_SPc	37..271	CDD:214473	52/265 (20%)
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	53/267 (20%)
prozb	NP_001313449.1	GLA	25..88	CDD:214503
		EGF_CA	89..125	CDD:238011
		FXa_inhibition	139..167	CDD:291342	3/8 (38%)
		Tryp_SPc	182..384	CDD:304450	48/245 (20%)
		Tryp_SPc	182..382	CDD:214473	47/243 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24278
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100